Lipid nanoparticles for drug delivery

L Xu, X Wang, Y Liu, G Yang… - Advanced …, 2022 - Wiley Online Library
Lipid nanoparticles have attracted significant interests in the last two decades, and have
achieved tremendous clinical success since the first clinical approval of Doxil in 1995. At the …

[HTML][HTML] Surface-modified lipid nanocarriers for crossing the blood-brain barrier (BBB): A current overview of active targeting in brain diseases

MI Teixeira, CM Lopes, MH Amaral, PC Costa - Colloids and Surfaces B …, 2023 - Elsevier
The blood-brain barrier (BBB) restricts the access of therapeutic agents to the brain,
complicating the treatment of neurological diseases, such as Alzheimer's disease (AD) …

Crossing the blood–brain barrier: recent advances in drug delivery to the brain

MM Patel, BM Patel - CNS drugs, 2017 - Springer
CNS disorders are on the rise despite advancements in our understanding of their
pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the …

Lactoferrin's anti-cancer properties: Safety, selectivity, and wide range of action

A Cutone, L Rosa, G Ianiro, MS Lepanto… - Biomolecules, 2020 - mdpi.com
Despite recent advances in cancer therapy, current treatments, including radiotherapy,
chemotherapy, and immunotherapy, although beneficial, present attendant side effects and …

Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier & targeting ligand

AO Elzoghby, MA Abdelmoneem, IA Hassanin… - Biomaterials, 2020 - Elsevier
Recent progress in protein-based nanomedicine, inspired by the success of Abraxane®
albumin-paclitaxel nanoparticles, have resulted in novel therapeutics used for treatment of …

Promising nanomedicines of shikonin for cancer therapy

C Yan, Q Li, Q Sun, L Yang, X Liu, Y Zhao… - International Journal …, 2023 - Taylor & Francis
Malignant tumor, the leading cause of death worldwide, poses a serious threat to human
health. For decades, natural product has been proven to be an essential source for novel …

Solid lipid nanoparticles for targeted natural and synthetic drugs delivery in high-incidence cancers, and other diseases: Roles of preparation methods, lipid …

HA Mohammed, RA Khan, V Singh, M Yusuf… - Nanotechnology …, 2023 - degruyter.com
Solid lipid nanoparticles (SLNs), the spheroidal-shaped, colloids state lipophilic-natured,
innovative nanoscale particulate materials, are being concurrently prepared by the quality …

A Review: Surface Engineering of Lipid‐Based Drug Delivery Systems

D Patel, J Solanki, MM Kher, A Azagury - Small, 2024 - Wiley Online Library
This review explores the evolution of lipid‐based nanoparticles (LBNPs) for drug delivery
(DD). Herein, LBNPs are classified into liposomes and cell membrane‐based nanoparticles …

Glycosylation changes in brain cancer

L Veillon, C Fakih, H Abou-El-Hassan… - ACS chemical …, 2018 - ACS Publications
Protein glycosylation is a posttranslational modification that affects more than half of all
known proteins. Glycans covalently bound to biomolecules modulate their functions by both …

Axial pharmaceutical properties of liposome in cancer therapy: Recent advances and perspectives

SH Kiaie, S Mojarad-Jabali, F Khaleseh… - International journal of …, 2020 - Elsevier
Abstract Evaluation of axial properties including preparation, surface functionalization, and
pharmacokinetics for delivery of pharmacologically active molecules and genes lead to …