This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …

Despite the remarkable cognitive power, humans are not alien beings living in their isolated
universe but part of the Earth's biosphere–a dynamic, intelligent system. The working of the …

This review considers computational psychiatry from a particular viewpoint: namely, a
commitment to explaining psychopathology in terms of pathophysiology. It rests on the …

This perspective describes predictive processing as a computational framework for
understanding cortical function in the context of emerging evidence, with a focus on sensory …

Perception and perceptual decision-making are strongly facilitated by prior knowledge about
the probabilistic structure of the world. While the computational benefits of using prior …

With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Fueled by developments in computational neuroscience, there has been increasing interest
in the underlying neurocomputational mechanisms of psychosis. One successful approach …

Hallucinations, perceptions in the absence of objectively identifiable stimuli, illustrate the
constructive nature of perception. Here, we highlight the role of prior beliefs as a critical …

We review a recent shift in conceptions of interoception and its relationship to hierarchical
inference in the brain. The notion of interoceptive inference means that bodily states are …