[HTML][HTML] Solid implantable devices for sustained drug delivery

E Magill, S Demartis, E Gavini, AD Permana… - Advanced Drug Delivery …, 2023 - Elsevier
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

Strategies to develop polymeric microneedles for controlled drug release

BZ Chen, YT He, ZQ Zhao, YH Feng, L Liang… - Advanced Drug Delivery …, 2023 - Elsevier
The remarkable appeal of microneedle controlled-release systems has captivated both the
academic community and pharmaceutical industry due to their great potential for achieving …

[HTML][HTML] Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer

H Abd-El-Azim, IA Tekko, A Ali, A Ramadan… - Journal of Controlled …, 2022 - Elsevier
Photodynamic therapy (PDT) to manage non-melanoma skin cancers has garnered great
attention over the past few years. Hypericin (Hy) is a potent lipid-soluble photosensitiser with …

Dissolvable polymer microneedles for drug delivery and diagnostics

M Ali, S Namjoshi, HAE Benson, Y Mohammed… - Journal of Controlled …, 2022 - Elsevier
Dissolvable transdermal microneedles (μND) are promising micro-devices used to transport
a wide selection of active compounds into the skin. To provide an effective therapeutic …

Dissolving microneedle patches loaded with amphotericin B microparticles for localised and sustained intradermal delivery: Potential for enhanced treatment of …

K Peng, LK Vora, IA Tekko, AD Permana… - Journal of Controlled …, 2021 - Elsevier
Fungal infections affect millions of people globally and are often unreceptive to conventional
topical or oral preparations because of low drug bioavailability at the infection site, lack of …

Advances of microneedles in biomedical applications

J Xu, D Xu, X Xuan, H He - Molecules, 2021 - mdpi.com
A microneedle (MN) is a painless and minimally invasive drug delivery device initially
developed in 1976. As microneedle technology evolves, microneedles with different shapes …

Novel bilayer microarray patch‐assisted long‐acting micro‐depot cabotegravir intradermal delivery for HIV pre‐exposure prophylaxis

IA Tekko, LK Vora, F Volpe‐Zanutto… - Advanced Functional …, 2022 - Wiley Online Library
Injectable long‐acting cabotegravir (CAB LA) is effective and safe for pre‐exposure HIV
prophylaxis. It is recently approved for clinical use in those at high risk of contracting HIV …

[HTML][HTML] Jet injectors: Perspectives for small volume delivery with lasers

J Schoppink, DF Rivas - Advanced drug delivery reviews, 2022 - Elsevier
Needle-free jet injectors have been proposed as an alternative to injections with hypodermic
needles. Currently, a handful of commercial needle-free jet injectors already exist. However …

Thermosensitive hydrogel microneedles for controlled transdermal drug delivery

JY Li, YH Feng, YT He, LF Hu, L Liang, ZQ Zhao… - Acta Biomaterialia, 2022 - Elsevier
By using the prominent merit of poly (N-isopropylacrylamide)(PNIPAm) that can reversibly
switch from a linear state to a coiled state with the change in temperature, in this work …

Research progress of advanced microneedle drug delivery system and its application in biomedicine

R Zhang, Q Miao, D Deng, J Wu, Y Miao, Y Li - Colloids and Surfaces B …, 2023 - Elsevier
Transdermal drug delivery is an effective way of drug delivery in addition to oral and
intravenous administration. Among them, microneedle administration is a new type of …