MicroRNAs (miRNAs) in neurodegenerative diseases

PT Nelson, WX Wang, BW Rajeev - Brain pathology, 2008‏ - Wiley Online Library
Aging‐related neurodegenerative diseases (NDs) are the culmination of many different
genetic and environmental influences. Prior studies have shown that RNAs are …

MicroRNomics: a newly emerging approach for disease biology

C Zhang - Physiological genomics, 2008‏ - journals.physiology.org
Genomic evidence reveals that gene expression in humans is precisely controlled in
cellular, tissue-type, temporal, and condition-specific manners. Completely understanding …

Cellular versus viral microRNAs in host–virus interaction

Z Ghosh, B Mallick, J Chakrabarti - Nucleic acids research, 2009‏ - academic.oup.com
MicroRNAs (miRNAs) mark a new paradigm of RNA-directed gene expression regulation in
a wide spectrum of biological systems. These small non-coding RNAs can contribute to the …

Bioinformatic identification and expression analysis of new microRNAs from Medicago truncatula

ZS Zhou, SQ Huang, ZM Yang - Biochemical and biophysical research …, 2008‏ - Elsevier
MicroRNAs (miRNAs) are a class of non-protein coding small RNAs that regulate gene post-
transcriptional expression in plants and animals. Although more than 1280 miRNAs in plant …

MicroRNome analysis unravels the molecular basis of SARS infection in bronchoalveolar stem cells

B Mallick, Z Ghosh, J Chakrabarti - PloS one, 2009‏ - journals.plos.org
Severe acute respiratory syndrome (SARS), caused by the coronavirus SARS-CoV, is an
acute infectious disease with significant mortality. A typical clinical feature associated with …

Integrated RNA-seq and sRNA-seq analysis identifies novel nitrate-responsive genes in Arabidopsis thaliana roots

EA Vidal, TC Moyano, G Krouk, MS Katari, M Tanurdzic… - BMC genomics, 2013‏ - Springer
Background Nitrate and other nitrogen metabolites can act as signals that regulate global
gene expression in plants. Adaptive changes in plant morphology and physiology triggered …

Robust expression of tumor suppressor miRNA's let-7 and miR-195 detected in plasma of Saudi female breast cancer patients

A Qattan, H Intabli, W Alkhayal, C Eltabache… - BMC cancer, 2017‏ - Springer
Background Female breast cancer is frequently diagnosed at a later stage and the leading
cause of cancer deaths world-wide. Levels of cell-free circulating microRNAs (miRNAs) can …

miRNAs: effectors of environmental influences on gene expression and disease

A Hudder, RF Novak - Toxicological sciences, 2008‏ - academic.oup.com
Discovered less than a decade ago, micro-RNAs (miRNAs) have emerged as important
regulators of gene expression in mammals. They consist of short nucleic acids, on …

Computational challenges in miRNA target predictions: to be or not to be a true target?

C Barbato, I Arisi, ME Frizzo, R Brandi… - BioMed Research …, 2009‏ - Wiley Online Library
All microRNA (miRNA) target—finder algorithms return lists of candidate target genes. How
valid is that output in a biological setting? Transcriptome analysis has proven to be a useful …

Altered expression profiles of microRNAs in a stable hepatitis B virus-expressing cell line

L Yan, Z Jian-Jun, C Wang, M Li, H **… - Chinese medical …, 2009‏ - journals.lww.com
Background MicroRNAs (miRNAs) are highly conserved small non-coding RNAs of 18–25
nucleotides (nt) that mediate post-transcriptional gene regulation. Hepatitis B virus (HBV) …