Clinical implementation of pharmacogenomics for personalized precision medicine: barriers and solutions

ME Klein, MM Parvez, JG Shin - Journal of pharmaceutical sciences, 2017‏ - Elsevier
Clinical implementation of pharmacogenomics (PGx) leads to personalized medicine, which
improves the efficacy, safety, and cost-effectiveness of treatments. Although PGx-based …

The development of large-scale de-identified biomedical databases in the age of genomics—principles and challenges

FK Dankar, A Ptitsyn, SK Dankar - Human genomics, 2018‏ - Springer
Contemporary biomedical databases include a wide range of information types from various
observational and instrumental sources. Among the most important features that unite …

Genetic data sharing and artificial intelligence in the era of personalized medicine based on a cross‐sectional analysis of the Saudi human genome program

AF Alrefaei, YM Hawsawi, D Almaleki, T Alafif… - Scientific Reports, 2022‏ - nature.com
The success of the Saudi Human Genome Program (SHGP), one of the top ten genomic
programs worldwide, is highly dependent on the Saudi population embracing the concept of …

Expanded newborn screening program in Saudi Arabia: incidence of screened disorders

M Alfadhel, A Al Othaim, S Al Saif… - … of paediatrics and …, 2017‏ - Wiley Online Library
Aim To address the implementation of the National Newborn Screening Program (NBS) in
Saudi Arabia and stratify the incidence of the screened disorders. Methods A retrospective …

Knowledge, perception, and application of pharmacogenomics among hospital pharmacists in Saudi Arabia

M Algahtani - Risk Management and Healthcare Policy, 2020‏ - Taylor & Francis
Introduction The accelerated transformation in the healthcare system supported by the Saudi
Vision 2030 makes the present the best time to start the real application of …

Assessment of healthcare professionals' knowledge, attitudes, and perceived challenges of clinical pharmacogenetic testing in Egypt

M Nagy, M Lynch, S Kamal, S Mohamed… - Personalized …, 2020‏ - Taylor & Francis
Aim: We evaluated healthcare practitioners' perspectives regarding clinical
pharmacogenetics in Cairo, Egypt. Materials & methods: We administered a paper-based …

Associations of recurrent miscarriages with chromosomal abnormalities, thrombophilia allelic polymorphisms and/or consanguinity in Saudi Arabia

RF Turki, M Assidi, HA Banni, HA Zahed, S Karim… - BMC medical …, 2016‏ - Springer
Background Recurrent pregnancy loss (RPL) or recurrent spontaneous abortion is an
obstetric complication that affects couples at reproductive age. Previous reports documented …

Assessment of knowledge about biobanking among healthcare students and their willingness to donate biospecimens

L Merdad, L Aldakhil, R Gadi, M Assidi, SY Saddick… - BMC Medical …, 2017‏ - Springer
Background Biobanks and biospecimen collections are becoming a primary means of
delivering personalized diagnostics and tailoring individualized therapeutics. This shift …

The road towards data integration in human genomics: players, steps and interactions

A Bernasconi, A Canakoglu… - Briefings in …, 2021‏ - academic.oup.com
Thousands of new experimental datasets are becoming available every day; in many cases,
they are produced within the scope of large cooperative efforts, involving a variety of …