Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression

B Guo, M Zhang, W Hao, Y Wang, T Zhang… - Translational …, 2023‏ - nature.com
Mood disorders are associated with elevated inflammation, and the reduction of symptoms
after multiple treatments is often accompanied by pro-inflammation restoration. A variety of …

New and emerging approaches to treat psychiatric disorders

KW Scangos, MW State, AH Miller, JT Baker… - Nature medicine, 2023‏ - nature.com
Psychiatric disorders are highly prevalent, often devastating diseases that negatively impact
the lives of millions of people worldwide. Although their etiological and diagnostic …

[HTML][HTML] Inflammation-related functional and structural dysconnectivity as a pathway to psychopathology

DR Goldsmith, M Bekhbat, ND Mehta, JC Felger - Biological psychiatry, 2023‏ - Elsevier
Findings from numerous laboratories and across neuroimaging modalities have consistently
shown that exogenous administration of cytokines or inflammatory stimuli that induce …

The role of inflammation in depression and fatigue

CH Lee, F Giuliani - Frontiers in immunology, 2019‏ - frontiersin.org
Depression and fatigue are conditions responsible for heavy global societal burden,
especially in patients already suffering from chronic diseases. These symptoms have been …

Psychoneuroimmunology: an introduction to immune-to-brain communication and its implications for clinical psychology

JE Bower, KR Kuhlman - Annual Review of Clinical Psychology, 2023‏ - annualreviews.org
Research conducted over the past several decades has revolutionized our understanding of
the role of the immune system in neural and psychological development and function across …

The role of inflammation and the gut microbiome in depression and anxiety

JM Peirce, K Alviña - Journal of neuroscience research, 2019‏ - Wiley Online Library
The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …

The neurobiology of interoception in health and disease

L Quadt, HD Critchley… - Annals of the New York …, 2018‏ - Wiley Online Library
Interoception is the sensing of internal bodily sensations. Interoception is an umbrella term
that encompasses (1) the afferent (body‐to‐brain) signaling through distinct neural and …

The role of inflammation in depression: from evolutionary imperative to modern treatment target

AH Miller, CL Raison - Nature reviews immunology, 2016‏ - nature.com
Crosstalk between inflammatory pathways and neurocircuits in the brain can lead to
behavioural responses, such as avoidance and alarm, that are likely to have provided early …

What does plasma CRP tell us about peripheral and central inflammation in depression?

JC Felger, E Haroon, TA Patel, DR Goldsmith… - Molecular …, 2020‏ - nature.com
Peripheral blood C-reactive protein (CRP) is a biomarker used clinically to measure
systemic inflammation and is reproducibly increased in a subset of patients with major …

[HTML][HTML] Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition

PC Calder, N Bosco, R Bourdet-Sicard, L Capuron… - Ageing research …, 2017‏ - Elsevier
Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …