Mild cognitive impairment (MCI) represents a transitional stage between healthy aging and
dementia, and affects 10–15% of the population over the age of 65. The failure of drug trials …

Importance Depression is common in individuals with mild cognitive impairment (MCI) and
may confer a higher likelihood of progression to dementia. Prevalence estimates of …

TREM 2 is an innate immune receptor expressed on the surface of microglia. Loss‐of‐
function mutations of TREM 2 are associated with increased risk of Alzheimer's disease …

Sex hormones have been implicated in neurite outgrowth, synaptogenesis, dendritic
branching, myelination and other important mechanisms of neural plasticity. Here we review …

Depression is caused by a change in neural activity resulting from an increase in glutamate
that drives excitatory neurons and may be responsible for the decline in the activity and …

Background: It has been reported that up to 42% of the population aged over 60 are affected
by mild cognitive impairment (MCI) worldwide. This study aims to investigate the prevalence …

There is increasing evidence of prodromal manifestation of neuropsychiatric symptoms in a
variety of neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's …

Depression is frequent in older individuals and is often associated with cognitive impairment
and increasing risk of subsequent dementia. Late-life depression (LLD) has a negative …

Introduction Biomarkers monitoring synaptic degeneration/loss would be valuable for
Alzheimer's disease (AD) diagnosis. Postsynaptic protein neurogranin may be a promising …

Objective This study explores the gender differences in the prevalence of mild cognitive
impairment (MCI) and the correlation between multiple influencing factors. Materials and …