Therapeutic potential of luteolin on cancer

M Çetinkaya, Y Baran - Vaccines, 2023 - mdpi.com
Cancer is a global concern, as the rate of incidence is increasing each year. The challenges
related to the current chemotherapy drugs, such as the concerns related to toxicity, turn to …

[HTML][HTML] Recent updates on source, biosynthesis, and therapeutic potential of natural flavonoid luteolin: a review

N Muruganathan, AR Dhanapal, V Baskar… - Metabolites, 2022 - mdpi.com
Nature gives immense resources that are beneficial to humankind. The natural compounds
present in plants provide primary nutritional values to our diet. Apart from food, plants also …

Immunopharmacological activities of luteolin in chronic diseases

L Huang, MY Kim, JY Cho - International Journal of Molecular Sciences, 2023 - mdpi.com
Flavonoids have been shown to have anti-oxidative effects, as well as other health benefits
(eg, anti-inflammatory and anti-tumor functions). Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) …

[HTML][HTML] Natural products and derivatives for breast cancer treatment: From drug discovery to molecular mechanism

J Zhang, Y Wu, Y Li, S Li, J Liu, X Yang, G **a, G Wang - Phytomedicine, 2024 - Elsevier
Background Breast cancer stands as the most common malignancy among women globally
and a leading cause of cancer-related mortality. Conventional treatments, such as surgery …

[HTML][HTML] Luteolin, a potent anticancer compound: from chemistry to cellular interactions and synergetic perspectives

H Singh Tuli, P Rath, A Chauhan, K Sak, D Aggarwal… - Cancers, 2022 - mdpi.com
Simple Summary Common flavonoid luteolin 3′, 4′, 5, 7-tetrahydroxyflavone has
immense potential to be utilized as a chemopreventive dietary molecule. According to …

Luteolin, a flavone ingredient: Anticancer mechanisms, combined medication strategy, pharmacokinetics, clinical trials, and pharmaceutical researches

M Shi, Z Chen, H Gong, Z Peng, Q Sun… - Phytotherapy …, 2024 - Wiley Online Library
Current pharmaceutical research is energetically excavating the pharmacotherapeutic role
of herb‐derived ingredients in multiple malignancies' targeting. Luteolin is one of the major …

Ginsenoside Rb1 inhibits cardiomyocyte autophagy via PI3K/Akt/mTOR signaling pathway and reduces myocardial ischemia/reperfusion injury

GW Qin, P Lu, L Peng, W Jiang - The American Journal of Chinese …, 2021 - World Scientific
Myocardial ischemia/reperfusion injury (MIRI) is the major cause of myocardial cell damage
in acute myocardial infarction, and its treatment remains a clinical challenge. Ginsenoside …

Anticancer activity of the plant flavonoid luteolin against preclinical models of various cancers and insights on different signalling mechanisms modulated

SA Ganai, FA Sheikh, ZA Baba, MA Mir… - Phytotherapy …, 2021 - Wiley Online Library
Various signaling mechanisms contribute significantly to the development of multiple
cancers. Small molecules with the potential of influencing a wide variety of molecular targets …

Revisiting luteolin: an updated review on its anticancer potential

A Rauf, P Wilairatana, PB Joshi, Z Ahmad, A Olatunde… - Heliyon, 2024 - cell.com
Numerous natural products found in our diet, such as polyphenols and flavonoids, can
prevent the progression of cancer. Luteolin, a natural flavone, present in significant amounts …

[HTML][HTML] Plants as a source of anticancer agents: From bench to bedside

WH Talib, S Daoud, AI Mahmod, RA Hamed, D Awajan… - Molecules, 2022 - mdpi.com
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …