Cell types are the basic functional units of an organism. Cell types exhibit diverse
phenotypic properties at multiple levels, making them challenging to define, categorize, and …

The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …

Spatial transcriptomic technologies promise to resolve cellular wiring diagrams of tissues in
health and disease, but comprehensive map** of cell types in situ remains a challenge …

Spatially resolved transcriptomic technologies are promising tools to study complex
biological processes such as mammalian embryogenesis. However, the imbalance between …

Human brain development is underpinned by cellular and molecular reconfigurations
continuing into the third decade of life. To reveal cell dynamics orchestrating neural …

The assembly of cortical circuits involves the generation and migration of interneurons from
the ventral to the dorsal forebrain,–, which has been challenging to study at inaccessible …

The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in
perception, cognition, emotion, and learning. We profiled∼ 1.3 million cells covering the …

Abstract In 2003 Rubenstein and Merzenich hypothesized that some forms of Autism (ASD)
might be caused by a reduction in signal-to-noise in key neural circuits, which could be the …

Throughout development, the brain transits from early highly synchronous activity patterns to
a mature state with sparse and decorrelated neural activity, yet the mechanisms underlying …

The brain is composed of complex networks of interacting neurons that express
considerable heterogeneity in their physiology and spiking characteristics. How does this …