The multidrug resistance phenomenon presents a major threat to the pharmaceutical
industry. This resistance is a common occurrence in several diseases and is mediated by …

P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse
structures out of cells, resulting in poor intestinal permeation and limited bioavailability …

Increasing life expectancy has led to an aging population, which has consequently
increased the prevalence of dementia. Alzheimer's disease (AD), the most common form of …

Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes
are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate …

Although there is convergent evidence for blood-brain barrier (BBB) dysfunction and
peripheral inflammation in schizophrenia (SZ) and bipolar disorder (BD), it is unknown …

Gastric cancer (GC) results from deregulated cell growth in the stomach. Despite significant
efforts and recent advancements in the treatment of gastric cancer, it remains a life …

Potential therapeutic actions of the cannabinoids delta-9-tetrahydrocannabinol (THC) and
cannabidiol (CBD) are based on their activity as analgesics, anti-emetics, anti-inflammatory …

Breast cancer remains one of the world's most dangerous diseases because of the difficulty
of finding cost-effective and specific targets for effective and efficient treatment methods. The …

Highlights•Oral route of administration is the preferred route for drug delivery.•Dosage form
designing plays an essential role in oral peptide delivery.•Preclinical and clinical aspects of …

Oral administration of insulin (INS) would represent a revolution in the treatment of diabetes,
considering that this route mimics the physiological dynamics of endogenous INS. Nano-and …