Coming together to define membrane contact sites

L Scorrano, MA De Matteis, S Emr, F Giordano… - Nature …, 2019 - nature.com
Close proximities between organelles have been described for decades. However, only
recently a specific field dealing with organelle communication at membrane contact sites …

The peroxisome: an update on mysteries 2.0

M Islinger, A Voelkl, HD Fahimi, M Schrader - Histochemistry and cell …, 2018 - Springer
Peroxisomes are key metabolic organelles, which contribute to cellular lipid metabolism, eg
the β-oxidation of fatty acids and the synthesis of myelin sheath lipids, as well as cellular …

Lipid droplet and peroxisome biogenesis occur at the same ER subdomains

AS Joshi, B Nebenfuehr, V Choudhary… - Nature …, 2018 - nature.com
Nascent lipid droplet (LD) formation occurs in the endoplasmic reticulum (ER) membrane
but it is not known how sites of biogenesis are determined. We previously identified ER …

Seipin and the membrane-sha** protein Pex30 cooperate in organelle budding from the endoplasmic reticulum

S Wang, FZ Idrissi, M Hermansson, A Grippa… - Nature …, 2018 - nature.com
Lipid droplets (LDs) and peroxisomes are ubiquitous organelles with central roles in
eukaryotic cells. Although the mechanisms involved in biogenesis of these organelles …

Comparative genomics of peroxisome biogenesis proteins: making sense of the PEX proteins

RLM Jansen, C Santana-Molina… - Frontiers in cell and …, 2021 - frontiersin.org
PEX genes encode proteins involved in peroxisome biogenesis and proliferation. Using a
comparative genomics approach, we clarify the evolutionary relationships between the 37 …

Peroxisome biogenesis, membrane contact sites, and quality control

JC Farré, SS Mahalingam, M Proietto, S Subramani - EMBO reports, 2019 - embopress.org
Peroxisomes are conserved organelles of eukaryotic cells with important roles in cellular
metabolism, human health, redox homeostasis, as well as intracellular metabolite transfer …

Hello from the other side: Membrane contact of lipid droplets with other organelles and subsequent functional implications

R Rakotonirina-Ricquebourg, V Costa… - Progress in Lipid …, 2022 - Elsevier
Lipid droplets (LDs) are ubiquitous organelles that play crucial roles in response to
physiological and environmental cues. The identification of several neutral lipid synthesizing …

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

SK Choudhry, ML Neal, S Li, AT Navare… - Journal of Cell …, 2023 - rupress.org
The nuclear pore complex (NPC) physically interacts with chromatin and regulates gene
expression. The Saccharomyces cerevisiae inner ring nucleoporin Nup170 has been …

Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers

CJ Stefan, WS Trimble, S Grinstein, G Drin, K Reinisch… - BMC biology, 2017 - Springer
Discoveries spanning several decades have pointed to vital membrane lipid trafficking
pathways involving both vesicular and non-vesicular carriers. But the relative contributions …

Key enzymes involved in the utilization of fatty acids by Saccharomyces cerevisiae: a review

Z Wang, C Su, Y Zhang, S Shangguan… - Frontiers in …, 2024 - frontiersin.org
Saccharomyces cerevisiae is a eukaryotic organism with a clear genetic background and
mature gene operating system; in addition, it exhibits environmental tolerance. Therefore, S …