Quality control of the mitochondrial proteome
Abstract Mitochondria contain about 1,000–1,500 proteins that fulfil multiple functions.
Mitochondrial proteins originate from two genomes: mitochondrial and nuclear. Hence …
Mitochondrial proteins originate from two genomes: mitochondrial and nuclear. Hence …
Lipids of mitochondria
SE Horvath, G Daum - Progress in lipid research, 2013 - Elsevier
A unique organelle for studying membrane biochemistry is the mitochondrion whose
functionality depends on a coordinated supply of proteins and lipids. Mitochondria are …
functionality depends on a coordinated supply of proteins and lipids. Mitochondria are …
New roles for mitochondrial proteases in health, ageing and disease
Recent advances in mitochondrial biology have revealed the high diversity and complexity
of proteolytic enzymes that regulate mitochondrial function. We have classified mitochondrial …
of proteolytic enzymes that regulate mitochondrial function. We have classified mitochondrial …
Phosphatidylethanolamine metabolism in health and disease
E Calzada, O Onguka, SM Claypool - … review of cell and molecular biology, 2016 - Elsevier
Phosphatidylethanolamine (PE) is the second most abundant glycerophospholipid in
eukaryotic cells. The existence of four only partially redundant biochemical pathways that …
eukaryotic cells. The existence of four only partially redundant biochemical pathways that …
Making heads or tails of phospholipids in mitochondria
Mitochondria are dynamic organelles whose functional integrity requires a coordinated
supply of proteins and phospholipids. Defined functions of specific phospholipids, like the …
supply of proteins and phospholipids. Defined functions of specific phospholipids, like the …
Metabolism and Regulation of Glycerolipids in the Yeast Saccharomyces cerevisiae
Due to its genetic tractability and increasing wealth of accessible data, the yeast
Saccharomyces cerevisiae is a model system of choice for the study of the genetics …
Saccharomyces cerevisiae is a model system of choice for the study of the genetics …
Mitochondrial proteases: multifaceted regulators of mitochondrial plasticity
Mitochondria are essential metabolic hubs that dynamically adapt to physiological demands.
More than 40 proteases residing in different compartments of mitochondria, termed …
More than 40 proteases residing in different compartments of mitochondria, termed …
A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria
S Hoppins, SR Collins, A Cassidy-Stone… - Journal of Cell …, 2011 - rupress.org
To broadly explore mitochondrial structure and function as well as the communication of
mitochondria with other cellular pathways, we constructed a quantitative, high-density …
mitochondria with other cellular pathways, we constructed a quantitative, high-density …
Mitochondrial quality control: a matter of life and death for neurons
EI Rugarli, T Langer - The EMBO journal, 2012 - embopress.org
Neuronal survival critically depends on the integrity and functionality of mitochondria. A
hierarchical system of cellular surveillance mechanisms protects mitochondria against …
hierarchical system of cellular surveillance mechanisms protects mitochondria against …
Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing
INTRODUCTION Protein quality control is essential for mitochondrial function, and
imbalances in this regulation are associated with numerous human diseases. YME1L is a …
imbalances in this regulation are associated with numerous human diseases. YME1L is a …