Stimuli-responsive polymer-based nanosystems for cancer theranostics

D Wei, Y Sun, H Zhu, Q Fu - ACS nano, 2023 - ACS Publications
Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …

A review on exosomes application in clinical trials: perspective, questions, and challenges

J Rezaie, M Feghhi, T Etemadi - Cell Communication and Signaling, 2022 - Springer
Background Exosomes are progressively known as significant mediators of cell-to-cell
communication. They convey active biomolecules to target cells and have vital functions in …

Cancer nanomedicine

SN Bhatia, X Chen, MA Dobrovolskaia… - Nature Reviews …, 2022 - nature.com
The field of cancer nanomedicine seeks to overcome the inherent shortcomings of
conventional cancer diagnostics and therapies. Yet despite the surge of interest in and …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J **ang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Nanoparticles with ultrasound-induced afterglow luminescence for tumour-specific theranostics

C Xu, J Huang, Y Jiang, S He, C Zhang… - Nature Biomedical …, 2023 - nature.com
Molecular imaging via afterglow luminescence minimizes tissue autofluorescence and
increases the signal-to-noise ratio. However, the induction of afterglow requires the prior …

Ultrasound-based micro-/nanosystems for biomedical applications

H Huang, Y Zheng, M Chang, J Song, L **a… - Chemical …, 2024 - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Smart nanomaterials in cancer theranostics: challenges and opportunities

BK Kashyap, VV Singh, MK Solanki, A Kumar… - ACS …, 2023 - ACS Publications
Cancer is ranked as the second leading cause of death globally. Traditional cancer
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …

Extracellular vesicles as a next-generation drug delivery platform

IK Herrmann, MJA Wood, G Fuhrmann - Nature nanotechnology, 2021 - nature.com
Extracellular-vesicle-based cell-to-cell communication is conserved across all kingdoms of
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …

New opportunities and old challenges in the clinical translation of nanotheranostics

PJ Gawne, M Ferreira, M Papaluca, J Grimm… - Nature Reviews …, 2023 - nature.com
Nanoparticle-based systems imbued with both diagnostic and therapeutic functions, known
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …