Integrating machine learning and biosensors in microfluidic devices: a review.

G Antonelli, J Filippi, M D'Orazio, G Curci… - Biosensors and …, 2024 - Elsevier
Microfluidic devices are increasingly widespread in the literature, being applied to numerous
exciting applications, from chemical research to Point-of-Care devices, passing through drug …

[HTML][HTML] Cells in the 3D Biomatrix on-chip: better mimicking the real micro-physiological system

M D'Orazio, J Filippi, G Antonelli, G Curci, P Casti… - Next Materials, 2024 - Elsevier
Recent advances in microfluidic technology and biomaterial science have augmented the
use of organ-on-chip (OoC) technology to closely mimic the human pathophysiology. Thus, it …

S3-VAE: A novel Supervised-Source-Separation Variational AutoEncoder algorithm to discriminate tumor cell lines in time-lapse microscopy images

P Casti, S Cardarelli, MC Comes, M D'Orazio… - Expert Systems with …, 2023 - Elsevier
The derivation of input–output relationships in deep learning architectures is mostly a black-
box process, in which uninformative or confounding factors might bias the classification …

Artificial intelligence assisted patient blood and urine droplet pattern analysis for non-invasive and accurate diagnosis of bladder cancer

R Demir, S Koc, DG Ozturk, S Bilir, Hİ Ozata… - Scientific Reports, 2024 - nature.com
Bladder cancer is one of the most common cancer types in the urinary system. Yet, current
bladder cancer diagnosis and follow-up techniques are time-consuming, expensive, and …

Machine learning approach for recognition and morphological analysis of isolated astrocytes in phase contrast microscopy

EV Yakovlev, IV Simkin, AA Shirokova, NA Kolotieva… - Scientific Reports, 2024 - nature.com
Astrocytes are glycolytically active cells in the central nervous system playing a crucial role
in various brain processes from homeostasis to neurotransmission. Astrocytes possess a …

A data-driven approach to detect upper limb functional use during daily life in breast cancer survivors using wrist-worn sensors

J Emmerzaal, B Filtjens, N Vets, B Vanrumste… - Scientific Reports, 2024 - nature.com
To gain insights into the impact of upper limb (UL) dysfunctions after breast cancer
treatment, this study aimed to develop a temporal convolutional neural network (TCN) to …

Prostate cancer detection using e-nose and AI for high probability assessment

JB Talens, J Pelegrí-Sebastiá, T Sogorb… - BMC medical informatics …, 2023 - Springer
This research aims to develop a diagnostic tool that can quickly and accurately detect
prostate cancer using electronic nose technology and a neural network trained on a dataset …

Single-cell classification based on label-free high-resolution optical data of cell adhesion kinetics

KD Kovacs, B Beres, N Kanyo, B Szabó, B Peter… - Scientific Reports, 2024 - nature.com
Selecting and isolating various cell types is a critical procedure in many applications,
including immune therapy, regenerative medicine, and cancer research. Usually, these …

[HTML][HTML] Automatic classification of HEp-2 specimens by explainable deep learning and Jensen-Shannon reliability index

A Mencattini, T Tocci, M Nuccetelli, M Pieri… - Artificial Intelligence in …, 2025 - Elsevier
Abstract The Anti-Nuclear Antibodies (ANA) test using Human Epithelial type 2 (HEp-2) cells
in the Indirect Immuno-Fluorescence (IIF) assay protocol is considered the gold standard for …

Domain adaptation to enhance (2+ 1) D CNN dynamic analysis of cell collective behavior in time-lapse microscopy videos

M D'Orazio, D Pastore, A Mencattini, J Filippi… - Neural Computing and …, 2024 - Springer
In recent years, 2D CNNs have excelled in analyzing single-frame video sequences,
prompting the evolution of standard architectures toward full 3D CNNs. This transition, while …