Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - Elsevier
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

An allostatic theory of oxytocin

DS Quintana, AJ Guastella - Trends in cognitive sciences, 2020 - cell.com
Oxytocin has garnered considerable interest for its role in social behavior, as well as for the
potential of intranasal administration to treat social difficulties. However, current theoretical …

[HTML][HTML] The effects of oxytocin on appetite regulation, food intake and metabolism in humans

L Kerem, EA Lawson - International Journal of Molecular Sciences, 2021 - mdpi.com
The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological
processes, including parturition, lactation, cell growth, wound healing, and social behavior …

Dietary fibre confers therapeutic effects in a preclinical model of Huntington's disease

C Gubert, G Kong, C Costello, CD Adams… - Brain, Behavior, and …, 2024 - Elsevier
Huntington's disease (HD) is a neurodegenerative disorder involving psychiatric, cognitive
and motor deficits, as well as peripheral symptoms, including gastrointestinal dysfunction …

Traumatic stress and the autonomic brain‐gut connection in development: Polyvagal theory as an integrative framework for psychosocial and gastrointestinal …

J Kolacz, KK Kovacic, SW Porges - Developmental …, 2019 - Wiley Online Library
A range of psychiatric disorders such as anxiety, depression, and post‐traumatic stress
disorder frequently co‐occur with functional gastrointestinal (GI) disorders. Risk of these …

New policies on skin-to-skin contact warrant an oxytocin-based perspective on perinatal health care

NJ Bergman - Frontiers in Psychology, 2024 - frontiersin.org
Background In 2023, the World Health Organization (WHO) published a Global Position
Paper on Kangaroo Mother Care (KMC), which is applicable to all countries worldwide: from …

Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling

HA Danhof, J Lee, A Thapa, RA Britton… - Gut Microbes, 2023 - Taylor & Francis
Intestinal microbes impact the health of the intestine and organs distal to the gut.
Limosilactobacillus reuteri is a human intestinal microbe that promotes normal gut transit …

Developmental programming of oxytocin through variation in early-life stress: Four meta-analyses and a theoretical reinterpretation

BJ Ellis, AJ Horn, CS Carter, MH van IJzendoorn… - Clinical Psychology …, 2021 - Elsevier
Despite evidence supporting a role for oxytocin (OT) in regulating social behavior,
surprisingly little is known about how this neuropeptide is calibrated during development …

Serotonin transporter variant drives preventable gastrointestinal abnormalities in development and function

KG Margolis, Z Li, K Stevanovic, V Saurman… - The Journal of clinical …, 2016 - jci.org
Autism spectrum disorder (ASD) is an increasingly common behavioral condition that
frequently presents with gastrointestinal (GI) disturbances. It is not clear, however, how gut …