Regulation of small gtpases by gefs, gaps, and gdis
J Cherfils, M Zeghouf - Physiological reviews, 2013 - journals.physiology.org
Small GTPases use GDP/GTP alternation to actuate a variety of functional switches that are
pivotal for cell dynamics. The GTPase switch is turned on by GEFs, which stimulate …
pivotal for cell dynamics. The GTPase switch is turned on by GEFs, which stimulate …
Endocytosis of viruses and bacteria
P Cossart, A Helenius - Cold Spring Harbor perspectives …, 2014 - cshperspectives.cshlp.org
Of the many pathogens that infect humans and animals, a large number use cells of the host
organism as protected sites for replication. To reach the relevant intracellular compartments …
organism as protected sites for replication. To reach the relevant intracellular compartments …
Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease
The aberrant activity of Ras homologous (Rho) family small GTPases (20 human members)
has been implicated in cancer and other human diseases. However, in contrast to the direct …
has been implicated in cancer and other human diseases. However, in contrast to the direct …
Infection strategies of enteric pathogenic Escherichia coli
Enteric Escherichia coli (E. coli) are both natural flora of humans and important pathogens
causing significant morbidity and mortality worldwide. Traditionally enteric E. coli have been …
causing significant morbidity and mortality worldwide. Traditionally enteric E. coli have been …
Typhoidal Salmonella: Distinctive virulence factors and pathogenesis
Although nontyphoidal Salmonella (NTS; including Salmonella Typhimurium) mainly cause
gastroenteritis, typhoidal serovars (Salmonella Typhi and Salmonella Paratyphi A) cause …
gastroenteritis, typhoidal serovars (Salmonella Typhi and Salmonella Paratyphi A) cause …
Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements
ARC Wong, JS Pearson, MD Bright… - Molecular …, 2011 - Wiley Online Library
The human pathogens enteropathogenic and enterohemorrhagic Escherichia coli (EPEC
and EHEC) share a unique mechanism of colonization that results from the concerted action …
and EHEC) share a unique mechanism of colonization that results from the concerted action …
Host cell targeting by enteropathogenic bacteria T3SS effectors
L Pinaud, PJ Sansonetti, A Phalipon - Trends in microbiology, 2018 - cell.com
Microbial pathogens possess a diversity of weapons that disrupt host homeostasis and
immune defenses, thus resulting in the establishment of infection. The best-characterized …
immune defenses, thus resulting in the establishment of infection. The best-characterized …
Prophages and satellite prophages are widespread in Streptococcus and may play a role in pneumococcal pathogenesis
Prophages (viral genomes integrated within a host bacterial genome) can confer various
phenotypic traits to their hosts, such as enhanced pathogenicity. Here we analyse> 1300 …
phenotypic traits to their hosts, such as enhanced pathogenicity. Here we analyse> 1300 …
LEEways: tales of EPEC, ATEC and EHEC
MA Schmidt - Cellular microbiology, 2010 - Wiley Online Library
Intestinal pathogenic Escherichia coli are a major cause of worldwide morbidity and
mortality. Currently seven intestinal pathovars are recognized causing a wide range of …
mortality. Currently seven intestinal pathovars are recognized causing a wide range of …
Manipulation of host membranes by bacterial effectors
H Ham, A Sreelatha, K Orth - Nature Reviews Microbiology, 2011 - nature.com
Bacterial pathogens interact with host membranes to trigger a wide range of cellular
processes during the course of infection. These processes include alterations to the …
processes during the course of infection. These processes include alterations to the …