Fracture toughness: bridging the gap between hip fracture and fracture risk assessment

D Dapaah, DR Martel, F Iranmanesh… - Current Osteoporosis …, 2023 - Springer
Abstract Purpose of Review This review surveys recent literature related to cortical bone
fracture mechanics and its application towards understanding bone fragility and hip …

Bone microarchitecture, biomechanical properties, and advanced glycation end-products in the proximal femur of adults with type 2 diabetes

L Karim, J Moulton, M Van Vliet, K Velie, A Robbins… - Bone, 2018 - Elsevier
Skeletal fragility is a major complication of type 2 diabetes mellitus (T2D), but there is a poor
understanding of mechanisms underlying T2D skeletal fragility. The increased fracture risk …

A review of conventional and novel treatments for osteoporotic hip replacements

F Alabdah, A Alshammari, A Hidalgo-Bastida… - Bioengineering, 2023 - mdpi.com
Introduction: Osteoporosis is a skeletal disease that severely affects the mechanical
properties of bone. It increases the porosity of cancellous bone and reduces the resistance …

[HTML][HTML] X-ray micro-computed tomography for nondestructive three-dimensional (3D) X-ray histology

OL Katsamenis, M Olding, JA Warner… - The American journal of …, 2019 - Elsevier
Historically, micro-computed tomography (μCT) has been considered unsuitable for
histologic analysis of unstained formalin-fixed, paraffin-embedded soft tissue biopsy …

Increasing fluoride content deteriorates rat bone mechanical properties

T Rezaee, ML Bouxsein, L Karim - Bone, 2020 - Elsevier
Elevation of bone fluoride levels due to drinking beverages with high fluoride content or
other means such as inhalation can result in skeletal fluorosis and lead to increased joint …

Effect of ribose incubation on physical, chemical, and mechanical properties of human cortical bone

M Unal, S Uppuganti, DY Dapaah, R Ahmed… - Journal of the …, 2023 - Elsevier
Raman spectroscopy (RS) is sensitive to the accumulation of advanced glycation end-
products (AGEs), and it measures matrix-sensitive properties that correlate with the fracture …

[HTML][HTML] Characterization of damage mechanisms in cortical bone: Quantification of fracture resistance, critical strains, and crack tortuosity

A Gustafsson, G Galteri, A Barakat, J Engqvist… - Journal of the …, 2024 - Elsevier
One step towards understanding bone fragility and degenerative diseases is to unravel the
links between fracture resistance and the compositional and structural characteristics of …

Phosphorylation of extracellular bone matrix proteins and its contribution to bone fragility

GE Sroga, D Vashishth - Journal of Bone and Mineral Research, 2018 - academic.oup.com
Phosphorylation of bone matrix proteins is of fundamental importance to all vertebrates
including humans. However, it is currently unknown whether increase or decline of total …

Computed tomography porosity and spherical indentation for determining cortical bone millimetre-scale mechanical properties

OR Boughton, S Ma, X Cai, L Yan, L Peralta… - Scientific reports, 2019 - nature.com
The cortex of the femoral neck is a key structural element of the human body, yet there is not
a reliable metric for predicting the mechanical properties of the bone in this critical region …

[HTML][HTML] Composition and micromechanical properties of the femoral neck compact bone in relation to patient age, sex and hip fracture occurrence

T Kochetkova, MS Hanke, M Indermaur, A Groetsch… - Bone, 2023 - Elsevier
Current clinical methods of bone health assessment depend to a great extent on bone
mineral density (BMD) measurements. However, these methods only act as a proxy for bone …