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Inflammatory processes in cardiovascular disease: a route to targeted therapies
Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …
Thrombosis formation on atherosclerotic lesions and plaque rupture
L Badimon, G Vilahur - Journal of internal medicine, 2014 - Wiley Online Library
Atherosclerosis is a silent chronic vascular pathology that is the cause of the majority of
cardiovascular ischaemic events. The evolution of vascular disease involves a combination …
cardiovascular ischaemic events. The evolution of vascular disease involves a combination …
Atherosclerotic carotid plaque composition and incident stroke and coronary events
D Bos, B Arshi, QJA van den Bouwhuijsen… - Journal of the American …, 2021 - jacc.org
Background Increasing evidence suggests that atherosclerotic plaque composition rather
than plaque size is linked to ischemic cardiovascular events, yet largescale population …
than plaque size is linked to ischemic cardiovascular events, yet largescale population …
Inflammation and stroke risk: a new target for prevention
New therapeutic approaches are required for secondary prevention of residual vascular risk
after stroke. Diverse sources of evidence support a causal role for inflammation in the …
after stroke. Diverse sources of evidence support a causal role for inflammation in the …
Vasa vasorum angiogenesis: key player in the initiation and progression of atherosclerosis and potential target for the treatment of cardiovascular disease
DG Sedding, EC Boyle, JAF Demandt… - Frontiers in …, 2018 - frontiersin.org
Plaque microvascularization and increased endothelial permeability are key players in the
development of atherosclerosis, from the initial stages of plaque formation to the occurrence …
development of atherosclerosis, from the initial stages of plaque formation to the occurrence …
Role of melatonin in controlling angiogenesis under physiological and pathological conditions
Q Ma, RJ Reiter, Y Chen - Angiogenesis, 2020 - Springer
Angiogenesis depends on proangiogenic and anti-angiogenic molecules that regulate
endothelial cell proliferation and migration. Well-regulated angiogenesis plays a pivotal role …
endothelial cell proliferation and migration. Well-regulated angiogenesis plays a pivotal role …
Prediction of progression of coronary artery disease and clinical outcomes using vascular profiling of endothelial shear stress and arterial plaque characteristics: the …
PH Stone, S Saito, S Takahashi, Y Makita… - Circulation, 2012 - Am Heart Assoc
Background—Atherosclerotic plaques progress in a highly individual manner. The purposes
of the Prediction of Progression of Coronary Artery Disease and Clinical Outcome Using …
of the Prediction of Progression of Coronary Artery Disease and Clinical Outcome Using …
The myth of the “vulnerable plaque” transitioning from a focus on individual lesions to atherosclerotic disease burden for coronary artery disease risk assessment
The cardiovascular science community has pursued the quest to identify vulnerable
atherosclerotic plaque in patients for decades, ho** to prevent acute coronary events …
atherosclerotic plaque in patients for decades, ho** to prevent acute coronary events …
Atherosclerotic plaque destabilization: mechanisms, models, and therapeutic strategies
Understanding the pathophysiology of atherogenesis and the progression of atherosclerosis
have been major goals of cardiovascular research during the previous decades. However …
have been major goals of cardiovascular research during the previous decades. However …
Microparticles, vascular function, and atherothrombosis
Membrane-shed submicron microparticles (MPs) are released after cell activation or
apoptosis. High levels of MPs circulate in the blood of patients with atherothrombotic …
apoptosis. High levels of MPs circulate in the blood of patients with atherothrombotic …