Drug consumption is driven by a drug's pharmacological effects, which are experienced as
rewarding, and is influenced by genetic, developmental, and psychosocial factors that …

The transition from adolescence to adulthood is characterized by improvements in higher-
order cognitive abilities and corresponding refinements of the structure and function of the …

This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

Converging evidence from electrophysiological, physiological and anatomical studies
suggests that abnormalities in the synchronized oscillatory activity of neurons may have a …

The role of the prefrontal cortex (PFC) takes center stage among unanswered questions in
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …

Cognitive control, the ability to voluntarily guide our behavior, continues to improve
throughout adolescence. Below we review the literature on age-related changes in brain …

Intrinsic, unconstrained neural activity exhibits rich spatial, temporal, and spectral
organization that undergoes continuous refinement from childhood through adolescence …

Brains systems undergo unique and specific dynamic changes at the cellular, circuit, and
systems level that underlie the transition to adult-level cognitive control. We integrate …

Dynamic changes in neurochemistry, fiber architecture, and tissue composition occur in the
adolescent brain. The course of these maturational processes is being charted with greater …

Background Adolescence is the phase of life between late childhood and adulthood.
Typically, adolescents seek diversion, new experiences, and strong emotions, sometimes …