With rapidly changing ecology, urbanization, climate change, increased travel and fragile
public health systems, epidemics will become more frequent, more complex and harder to …

Social and cultural forces shape almost every aspect of infectious disease transmission in
human populations, as well as our ability to measure, understand, and respond to …

Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

Zanzibar has made significant progress toward malaria elimination, but recent stagnation
requires novel approaches. We developed a highly multiplexed droplet digital PCR (ddPCR) …

Background: National Malaria Control Programmes (NMCPs) currently make limited use of
parasite genetic data. We have developed GenRe-Mekong, a platform for genetic …

Recent decades have witnessed several infectious disease outbreaks, including the
coronavirus disease (COVID-19) pandemic, which had catastrophic impacts on societies …

Genomic epidemiology has guided research and policy for various viral pathogens and
there has been a parallel effort towards using genomic epidemiology to combat diseases …

Background Targeted next-generation sequencing offers the potential for consistent, deep
coverage of information-rich genomic regions to characterize polyclonal Plasmodium …

An essential step toward reconstructing pathogen transmission and answering
epidemiologically relevant questions from genomic data is obtaining pairwise genetic …

Motivation Malaria parasite genetic data can provide insight into parasite phenotypes,
evolution, and transmission. However, estimating key parameters such as allele …