Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N **e… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Carrier-free nanomedicines for cancer treatment

LH Liu, XZ Zhang - Progress in Materials Science, 2022 - Elsevier
The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy

W Zhang, X Hu, Q Shen, D **ng - Nature communications, 2019 - nature.com
Cancer cells exhibit slightly elevated levels of reactive oxygen species (ROS) compared with
normal cells, and approximately 90% of intracellular ROS is produced in mitochondria. In …

Platinum prodrug nanoparticles with COX‐2 inhibition amplify pyroptosis for enhanced chemotherapy and immune activation of pancreatic cancer

B Yu, Y Wang, T Bing, Y Tang, J Huang… - Advanced …, 2024 - Wiley Online Library
Pyroptosis, an emerging mechanism of programmed cell death, holds great potential to
trigger a robust antitumor immune response. Platinum‐based chemotherapeutic agents can …

Research progress on self-assembled nanodrug delivery systems

L Qiao, H Yang, S Gao, L Li, X Fu, Q Wei - Journal of materials …, 2022 - pubs.rsc.org
In recent years, nanodrug delivery systems have attracted increasing attention due to their
advantages, such as high drug loading, low toxicity and side effects, improved …

Recent advances on reactive oxygen species-responsive delivery and diagnosis system

H Ye, Y Zhou, X Liu, Y Chen, S Duan, R Zhu… - …, 2019 - ACS Publications
Reactive oxygen species (ROS) play crucial roles in biological metabolism and intercellular
signaling. However, ROS level is dramatically elevated due to abnormal metabolism during …

Advanced functional polymer materials

K Wang, K Amin, Z An, Z Cai, H Chen… - Materials Chemistry …, 2020 - pubs.rsc.org
The research on advanced functional polymers is being driven by the fast-growing demand
for new functional materials that can be used in revolutionary technologies. Polymers can be …

Biomimetic dendrimer–peptide conjugates for early multi‐target therapy of Alzheimer's disease by inflammatory microenvironment modulation

P Liu, T Zhang, Q Chen, C Li, Y Chu, Q Guo… - Advanced …, 2021 - Wiley Online Library
Current therapeutic strategies for Alzheimer's disease (AD) treatments mainly focus on β‐
amyloid (Aβ) targeting. However, such therapeutic strategies have limited clinical outcomes …

Encapsulation of Lactobacillus rhamnosus in Hyaluronic Acid-Based Hydrogel for Pathogen-Targeted Delivery to Ameliorate Enteritis

Y **ao, C Lu, Y Liu, LL Kong, H Bai, H Mu… - … applied materials & …, 2020 - ACS Publications
Probiotics were found to be effective in ameliorating the microbial dysbiosis and
inflammation caused by intestinal pathogens. However, biological challenges encountered …

Ferroptosis: challenges and opportunities for nanomaterials in cancer therapy

Q Liu, Y Zhao, H Zhou, C Chen - Regenerative Biomaterials, 2023 - academic.oup.com
Ferroptosis, a completely new form of regulated cell death, is mainly caused by an
imbalance between oxidative damage and reductive protection and has shown great anti …