A pragmatic guide to enrichment strategies for mass spectrometry–based glycoproteomics

NM Riley, CR Bertozzi, SJ Pitteri - Molecular & Cellular Proteomics, 2021 - ASBMB
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Recent advances in analytical approaches for glycan and glycopeptide quantitation

DG Delafield, L Li - Molecular & Cellular Proteomics, 2021 - ASBMB
Growing implications of glycosylation in physiological occurrences and human disease have
prompted intensive focus on revealing glycomic perturbations through absolute and relative …

[HTML][HTML] Hydrophilic interaction chromatography–mass spectrometry for metabolomics and proteomics: state-of-the-art and current trends

I Kohler, M Verhoeven, R Haselberg… - Microchemical Journal, 2022 - Elsevier
Among all the–omics approaches, proteomics and metabolomics have received increased
attention over the last decade. Both approaches have reached a certain level of maturity …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

DJ Harvey - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Mucinomics as the next frontier of mass spectrometry

V Rangel-Angarita, SA Malaker - ACS chemical biology, 2021 - ACS Publications
Mucin-domain glycoproteins comprise a class of proteins whose densely O-glycosylated
mucin domains adopt a secondary structure with unique biophysical and biochemical …

The “sugar‐coated bullets” of cancer: Tumor‐derived exosome surface glycosylation from basic knowledge to applications

S Lin, S Zhou, T Yuan - Clinical and Translational Medicine, 2020 - Wiley Online Library
Scientific interest in exosomes has exploded in recent decades. In 1990 only three articles
were published on exosomes, while over 1,700 have already been published half‐way into …

Design of a spiropyran-based smart adsorbent with dual response: focusing on highly efficient enrichment of phosphopeptides

Y Zhao, Z Li, J Ma, Q Jia - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Smart responsive materials have attractive application prospects due to their tunable
behaviors. In this work, we design novel spiropyran (SP)-based magnetic nanoparticles …

Boost-DiLeu: Enhanced Isobaric N,N-Dimethyl Leucine Tagging Strategy for a Comprehensive Quantitative Glycoproteomic Analysis

D Wang, M Ma, J Huang, TJ Gu, Y Cui, M Li… - Analytical …, 2022 - ACS Publications
Intact glycopeptide analysis has been of great interest because it can elucidate glycosylation
site information and glycan structural composition at the same time. However, mass …

Peak filtering, peak annotation, and wildcard search for glycoproteomics

A Roushan, GM Wilson, D Kletter, KI Sen… - Molecular & Cellular …, 2021 - ASBMB
Glycopeptides in peptide or digested protein samples pose a number of analytical and
bioinformatics challenges beyond those posed by unmodified peptides or peptides with …

Recent advancements in glycoproteomic studies: Glycopeptide enrichment and derivatization, characterization of glycosylation in SARS CoV2, and interacting …

I Pujić, H Perreault - Mass spectrometry reviews, 2022 - Wiley Online Library
Proteomics studies allow for the determination of the identity, amount, and interactions of
proteins under specific conditions that allow the biological state of an organism to ultimately …