The purpose of the study was to develop an SNEDDS to improve the solubility and
bioavailability of pitavastatin. The solubility of pitavastatin in different oils, surfactants, and co …

Supercritical carbon dioxide (scCO 2) application in the pharmaceutical industry is still
undeveloped regardless of significant research interests in this processing medium shown …

The study aimed to enhance the solubility, dissolution, and oral bioavailability of
standardized Piper longum fruits ethanolic extract (PLFEE) via fourth-generation ternary …

The aim of our research was to improve the solubility and antioxidant activity of pterostilbene
(PTR) by develo** a novel amorphous solid dispersion (ASD) with Soluplus®(SOL). DSC …

Cannabinoids: cannabidiol (CBD), cannabidiolic acid (CBDA), and cannabichromene (CBC)
are lipophilic compounds with limited water solubility, resulting in challenges related to their …

Additive manufacturing of pharmaceutical formulations offers advanced micro-structure
control of oral solid dose (OSD) forms targeting not only customised dosing of an active …

SD (solid dispersion) technology is one of the well-recognized solubility enhancement
methods; but the use of versatile carriers in ASD (amorphous SD) to achieve the added …

Simvastatin (SIM) is a potent lipid-lowering drug used to control hyper-cholesterolemia and
prevent cardiovascular diseases. SIM presents low oral bioavailability (5%) because of its …

Microparticles (MPs) and amorphous solid dispersions (SDs) are effective methods to
improve the dissolution of insoluble drugs. However, stability is a concern for these two high …

Baicalein (BAI) is a natural flavonoid with antioxidant, antitumor and antibacterial properties.
However, the bioavailability of BAI was limited due to low solubility. This study aims to …