Anti-obesity drug discovery: advances and challenges

TD Müller, M Blüher, MH Tschöp… - Nature Reviews Drug …, 2022 - nature.com
Enormous progress has been made in the last half-century in the management of diseases
closely integrated with excess body weight, such as hypertension, adult-onset diabetes and …

Genetics and neurobiology of eating disorders

CM Bulik, JRI Coleman, JA Hardaway… - Nature …, 2022 - nature.com
Eating disorders (anorexia nervosa, bulimia nervosa and binge-eating disorder) are a
heterogeneous class of complex illnesses marked by weight and appetite dysregulation …

The science behind the academy for eating disorders' nine truths about eating disorders

K Schaumberg, E Welch, L Breithaupt… - European Eating …, 2017 - Wiley Online Library
Abstract Objective In 2015, the Academy for Eating Disorders collaborated with international
patient, advocacy, and parent organizations to craft the 'Nine Truths About Eating Disorders' …

Gut microbiota composition in male rat models under different nutritional status and physical activity and its association with serum leptin and ghrelin levels

MI Queipo-Ortuño, LM Seoane, M Murri, M Pardo… - PloS one, 2013 - journals.plos.org
Background Several evidences indicate that gut microbiota is involved in the control of host
energy metabolism. Objective To evaluate the differences in the composition of gut …

Anti-obesity therapy: from rainbow pills to polyagonists

TD Müller, C Clemmensen, B Finan, RD DiMarchi… - Pharmacological …, 2018 - Elsevier
With their ever-growing prevalence, obesity and diabetes represent major health threats of
our society. Based on estimations by the World Health Organization, approximately 300 …

Identification and management of eating disorders in children and adolescents

DS Rosen, Committee on Adolescence - Pediatrics, 2010 - publications.aap.org
The incidence and prevalence of eating disorders in children and adolescents has
increased significantly in recent decades, making it essential for pediatricians to consider …

Psychological aspects of infertility. A systematic review

F Szkodziak, J Krzyżanowski… - Journal of International …, 2020 - journals.sagepub.com
Objective Fertility may be defined as a capacity to conceive and produce offspring. Infertility
is characterized by failure to establish a clinical pregnancy after 12 months of regular and …

Obstetric and gynecologic problems associated with eating disorders

MC Kimmel, EH Ferguson, S Zerwas… - … journal of eating …, 2016 - Wiley Online Library
Objective This article summarizes the literature on obstetric and gynecologic complications
associated with eating disorders. Method We performed a comprehensive search of the …

Adolescent eating disorders: definitions, symptomatology, epidemiology and comorbidity

B Herpertz-Dahlmann - Child and adolescent psychiatric clinics of North …, 2009 - Elsevier
Eating disorders have morbidity and mortality rates that are among the highest of any mental
disorders and are associated with significant functional impairment. This article provides an …

Novel treatments for anorexia nervosa: insights from neuroplasticity research

JL Keeler, C Kan, J Treasure… - … Eating Disorders Review, 2024 - Wiley Online Library
Objective Treatment for anorexia nervosa (AN) remains challenging; there are no approved
psychopharmacological interventions and psychotherapeutic strategies have variable …