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Context-specific regulation of extracellular vesicle biogenesis and cargo selection
AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …
other cells. An important aspect of cell–cell communication involves secretion of molecules …
Extracellular vesicles and nanoparticles: emerging complexities
The study of extracellular vesicles (EVs) and nanoparticles (NPs) is rapidly expanding
because recent discoveries have revealed a much greater complexity and diversity than was …
because recent discoveries have revealed a much greater complexity and diversity than was …
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …
origin and change the functions and phenotypes of other cells. These features indicate …
Clinical applications of stem cell-derived exosomes
F Tan, X Li, Z Wang, J Li, K Shahzad… - Signal transduction and …, 2024 - nature.com
Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …
certain diseases more successfully than conventional surgery, it nevertheless comes with …
Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
The roles of extracellular vesicles in the immune system
EI Buzas - Nature Reviews Immunology, 2023 - nature.com
The twenty-first century has witnessed major developments in the field of extracellular
vesicle (EV) research, including significant steps towards defining standard criteria for the …
vesicle (EV) research, including significant steps towards defining standard criteria for the …
A review on exosomes application in clinical trials: perspective, questions, and challenges
Background Exosomes are progressively known as significant mediators of cell-to-cell
communication. They convey active biomolecules to target cells and have vital functions in …
communication. They convey active biomolecules to target cells and have vital functions in …
Single test-based diagnosis of multiple cancer types using Exosome-SERS-AI for early stage cancers
Early cancer detection has significant clinical value, but there remains no single method that
can comprehensively identify multiple types of early-stage cancer. Here, we report the …
can comprehensively identify multiple types of early-stage cancer. Here, we report the …
Recent advances in extracellular vesicles for therapeutic cargo delivery
Exosomes, which are nanosized vesicles secreted by cells, are attracting increasing interest
in the field of biomedical research due to their unique properties, including biocompatibility …
in the field of biomedical research due to their unique properties, including biocompatibility …
Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials
A Lotfy, NM AboQuella, H Wang - Stem Cell Research & Therapy, 2023 - Springer
Mesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …