Bacteria produce a wide range of exopolysaccharides which are synthesized via different
biosynthesis pathways. The genes responsible for synthesis are often clustered within the …

Hyaluronic acid (HA) is a naturally formed acidic mucopolysaccharide, with excellent
moisturising properties and used widely in the medicine, cosmetics, and food industries. The …

Three mammalian hyaluronan synthase genes, HAS1, HAS2, and HAS3, have recently
been cloned. In this study, we characterized and compared the enzymatic properties of …

Abstracts Hyaluronic acid (HA) is a commercially valuable medical biopolymer increasingly
produced through microbial fermentation. Viscosity limits product yield and the focus of …

Low-molecular-weight hyaluronan (LMW-HA) has attracted much attention because of its
many potential applications. Here, we efficiently produced specific LMW-HAs from sucrose …

The hyaluronan (HA) matrix in the tissue microenvironment is crucial for maintaining
homeostasis by regulating inflammatory signalling, endothelial–mesenchymal transition and …

Hyaluronan (or hyaluronic acid or hyaluronate; HA) is a polysaccharide found in the
extracellular matrix of vertebrate tissues and in the surface coating of certain Streptococcus …

Hyaluronic acid (HA) is a high-value biopolymer that is produced in large scales using
attenuated strains ofgroup C streptococci. However, due to the pathogenicity and fastidious …

Hyaluronan-rich matrices are abundant in ECM and are involved in biological processes,
such as cell growth and migration. Hyaluronan is synthesized by the hyaluronan synthase …

Hyaluronan (HA) biosynthesis has been studied for over six decades, but our understanding
of the biochemical details of how HA synthase (HAS) assembles HA is still incomplete. Class …