Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

[HTML][HTML] Recent developments in molecular modeling tools and applications related to pharmaceutical and biomedical research

P Peluso, B Chankvetadze - Journal of Pharmaceutical and Biomedical …, 2024 - Elsevier
In modern pharmaceutical and biomedical research, molecular modeling represents a
useful tool to explore processes and their mechanistic bases at the molecular level …

Chiral separation by capillary electrokinetic chromatography with hydrophobic deep eutectic solvents as pseudo-stationary phases

Y Xu, A Li, S Xue, S Ding, Q Zhang - Talanta, 2023 - Elsevier
This study demonstrated for the first time that hydrophobic deep eutectic solvents (HDESs)
can be used in capillary electrophoresis (CE) for chiral separations. We found that the an …

Molecular dynamics simulations of amylose-and cellulose-based selectors and related enantioseparations in liquid phase chromatography

R Dallocchio, A Dessì, B Sechi, P Peluso - Molecules, 2023 - mdpi.com
In the last few decades, theoretical and technical advancements in computer facilities and
computational techniques have made molecular modeling a useful tool in liquid-phase …

[HTML][HTML] Unravelling dispersion forces in liquid-phase enantioseparation. Part I: Impact of ferrocenyl versus phenyl groups

B Sechi, A Dessì, R Dallocchio, N Tsetskhladze… - Analytica Chimica …, 2023 - Elsevier
Background Highly ordered chiral secondary structures as well as multiple (tunable)
recognition sites are the keys to success of polysaccharide carbamate-based chiral …

The role of deep eutectic solvents in chiral capillary electrokinetic chromatography: A comparative study based on α-cyclodextrin chiral selector

A Li, S Ren, C Teng, H Liu, Q Zhang - Journal of Molecular Liquids, 2022 - Elsevier
Deep eutectic solvents (DESs) are emerging as potential candidates as additives/modifiers
in chiral electrokinetic chromatography (EKC). However, the true role of DESs in the chiral …

Separation of undeuterated and partially deuterated enantioisotopologues of some amphetamine derivatives on achiral and polysaccharide-based chiral columns in …

G Kobidze, G Sprega, G Daziani, A Balloni… - … of Chromatography A, 2024 - Elsevier
The different behavior of enantiomers of chiral compounds in non-isotropic environments
(among them in living organism) is well known. On the other hand, the importance of a …

Separation of tetrahydrozoline enantiomers in capillary electrophoresis with cyclodextrin-type chiral selectors and investigation of chiral recognition mechanisms

A Gogolashvili, K Lomsadze, L Chankvetadze… - … of Chromatography A, 2021 - Elsevier
The recognition power and affinity pattern of various cyclodextrins (CD) towards the
enantiomers of tetrahydrozoline (THZ) were studied using capillary electrophoresis (CE). As …

Virtual chiral recognition of eugenol derivatives on amylose tris (3-chloro-5-methylphenylcarbamate) chiral stationary phase in unusual normal-phase mode

G Pulitelli, FR Mammone, D Sadutto, D Tanini… - Analytica Chimica …, 2023 - Elsevier
Chromatographic enantioseparation on polysaccharide-based chiral stationary phases has
undergone explosive development over the last three decades as a method for separating …

[HTML][HTML] Chiral separation of oxazolidinone analogues by liquid chromatography on polysaccharide stationary phases using polar organic mode

M Dobó, M Foroughbakhshfasaei, P Horváth… - … of Chromatography A, 2022 - Elsevier
The enantioseparation of four oxazolidinone and one biosimilar thiazolidine derivatives was
performed on seven different polysaccharide-type chiral stationary phases (Lux Amylose-1 …