[HTML][HTML] Mechanism of action and in vivo role of platelet-derived growth factor
CH Heldin, B Westermark - Physiological reviews, 1999 - journals.physiology.org
Platelet-derived growth factor (PDGF) is a major mitogen for connective tissue cells and
certain other cell types. It is a dimeric molecule consisting of disulfide-bonded, structurally …
certain other cell types. It is a dimeric molecule consisting of disulfide-bonded, structurally …
Inflammation in kidney repair: Mechanism and therapeutic potential
Y Fu, Y ** CKD, but the mechanisms linking AKI to CKD remain
unclear. Because proximal tubule injury is the mainstay of AKI, we postulated that proximal …
unclear. Because proximal tubule injury is the mainstay of AKI, we postulated that proximal …
[HTML][HTML] Myofibroblast differentiation during fibrosis: role of NAD (P) H oxidases
JL Barnes, Y Gorin - Kidney international, 2011 - Elsevier
Progression of fibrosis involves interstitial hypercellularity, matrix accumulation, and atrophy
of epithelial structures, resulting in loss of normal function and ultimately organ failure. There …
of epithelial structures, resulting in loss of normal function and ultimately organ failure. There …
Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study.
K Zhang, MD Rekhter, D Gordon… - The American journal of …, 1994 - ncbi.nlm.nih.gov
Appearance of contractile filament-laden stromal cells or myofibroblasts is a characteristic of
lung fibrotic lesions. The role of these cells in fibrosis and their cytoskeletal phenotype are …
lung fibrotic lesions. The role of these cells in fibrosis and their cytoskeletal phenotype are …
[HTML][HTML] Vascular pathobiology in chronic liver disease and cirrhosis–current status and future directions
Y Iwakiri, V Shah, DC Rockey - Journal of hepatology, 2014 - Elsevier
Chronic liver disease is associated with remarkable alterations in the intra-and extrahepatic
vasculature. Because of these changes, the fields of liver vasculature and portal …
vasculature. Because of these changes, the fields of liver vasculature and portal …
Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats
Fructose intake has been recently linked to the epidemic of metabolic syndrome and, in turn,
the metabolic syndrome has been epidemiologically linked with renal progression. The …
the metabolic syndrome has been epidemiologically linked with renal progression. The …