Glioblastoma multiforme (GBM) is a WHO grade IV glioma and the most common malignant,
primary brain tumor with a 5-year survival of 7.2%. Its highly infiltrative nature, genetic …

Brain metastases are a very common manifestation of cancer that have historically been
approached as a single disease entity given the uniform association with poor clinical …

The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia,
ie, heating to 39–45° C to induce sensitization to radiotherapy and chemotherapy, and …

An estimated 20% of all patients with cancer will develop brain metastases, with the majority
of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma …

Brain metastases occur commonly in patients with advanced solid malignancies. Yet, less is
known about brain metastases than cancer-related entities of similar incidence. Advances in …

Despite significant advances in research, the prognosis for both primary and secondary
brain cancers remains poor. The blood-brain barrier (BBB) is a complex and unique semi …

The use of radiotherapy, either in the form of stereotactic radiosurgery (SRS) or whole-brain
radiotherapy (WBRT), remains the cornerstone for the treatment of brain metastases (BM) …

Abstract Introduction Laser Interstitial Thermotherapy (LITT; also known as Stereotactic
Laser Ablation or SLA), is a minimally invasive treatment modality that has recently gained …

Hyperthermia therapy (HT) of cancer is a well-known treatment approach. With the advent of
new technologies, HT approaches are now important for the treatment of brain tumors. We …

Brain metastasis (BM), the most common adult brain tumor, develops in 20% to 40% of
patients with late‐stage cancer and traditionally are associated with a poor prognosis. The …