Background Chronic non‐cancer pain, a disabling and distressing condition, is common in
adults. It is a global public health problem and economic burden on health and social care …

Background This review is an update of'Topical capsaicin (high concentration) for chronic
neuropathic pain in adults' last updated in Issue 2, 2013. Topical creams with capsaicin are …

1. Background Chronic pain is very frequent 7, 9, 13 and one of the most common reasons
to seek medical attention. 18, 19 It is a major contributor to the global burden of disease, 8 …

Background Chronic pain is among the most burdensome conditions. Its prevalence ranges
between 12% and 30% in Europe, with an estimated 21% among Austrian adults. The …

Background Osteoarthritis (OA) is a leading cause of pain and disability, which may be a
source of productivity losses. The objectives of this study were to describe the impact of OA …

Introduction Chronic pain (CP) negatively impacts the lives of almost 2 billion people
worldwide, including approximately 37% of adults in Portugal. As most of these patients are …

Background: Chronic pain is a prevalent and distressing condition caused by an unceasing
pain lasting more than 3 months or a pain that persists beyond the normal healing time …

The magnitude of the cost of chronic pain has been a matter of concern in many countries
worldwide. The high prevalence, the cost it implies for the health system, productivity, and …

Objectives Randomized clinical trials are used to evaluate the efficacy of various pain
treatments individually, while a limited number of observational studies have portrayed the …

Chronic pain is a major public health problem and an economic burden worldwide.
However, its underlying pathological mechanisms remain unclear. MicroRNAs (miRNAs) are …