Atopic dermatitis endotypes and implications for targeted therapeutics

T Czarnowicki, H He, JG Krueger… - Journal of Allergy and …, 2019‏ - Elsevier
Recent research advancements indicate that atopic dermatitis (AD) is a complex disease
characterized by different subtypes/phenotypes based on age, disease chronicity, ethnicity …

[HTML][HTML] Precision medicine in patients with allergic diseases: airway diseases and atopic dermatitis—PRACTALL document of the European Academy of Allergy and …

A Muraro, RF Lemanske Jr, PW Hellings… - Journal of allergy and …, 2016‏ - Elsevier
In this consensus document we summarize the current knowledge on major asthma, rhinitis,
and atopic dermatitis endotypes under the auspices of the PRACTALL collaboration …

Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study

AK Waljee, MAM Rogers, P Lin, AG Singal, JD Stein… - bmj, 2017‏ - bmj.com
Objective To determine the frequency of prescriptions for short term use of oral
corticosteroids, and adverse events (sepsis, venous thromboembolism, fractures) associated …

The role of the skin microbiome in atopic dermatitis: a systematic review

RD Bjerre, J Bandier, L Skov… - British Journal of …, 2017‏ - academic.oup.com
Dysbiosis is a hallmark of atopic dermatitis (AD). The composition of skin microbiome
communities and the causality of dysbiosis in eczema have not been well established. The …

Mediators of chronic pruritus in atopic dermatitis: getting the itch out?

NK Mollanazar, PK Smith, G Yosipovitch - Clinical reviews in allergy & …, 2016‏ - Springer
For centuries, itch was categorized as a submodality of pain. Recent research over the last
decade has led to the realization that itch is in fact a separate and distinct, albeit closely …

[HTML][HTML] Skin colonization by Staphylococcus aureus precedes the clinical diagnosis of atopic dermatitis in infancy

P Meylan, C Lang, S Mermoud, A Johannsen… - Journal of Investigative …, 2017‏ - Elsevier
Atopic dermatitis (AD) has a well-established association with skin colonization or infection
by Staphylococcus aureus, which can exacerbate the disease. However, a causal …

The role of air pollutants in atopic dermatitis

K Ahn - Journal of Allergy and Clinical Immunology, 2014‏ - Elsevier
Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease and a growing health
concern, especially in children, because of its high prevalence and associated low quality of …

Atopic dermatitis: a practice parameter update 2012

L Schneider, S Tilles, P Lio, M Boguniewicz… - Journal of Allergy and …, 2013‏ - Elsevier
This parameter was developed by the Joint Task Force on Practice Parameters,
representing the American Academy of Allergy, Asthma & Immunology (AAAAI); the …

New concept of the pathogenesis of atopic dermatitis: interplay among the barrier, allergy, and pruritus as a trinity

K Kabashima - Journal of dermatological science, 2013‏ - Elsevier
Atopic dermatitis (AD) is a common skin condition, characterized by a complex,
heterogeneous pathogenesis, including skin barrier dysfunctions, allergy/immunology, and …

Understanding the immune landscape in atopic dermatitis: The era of biologics and emerging therapeutic approaches

M Moyle, F Cevikbas, JL Harden… - Experimental …, 2019‏ - Wiley Online Library
Atopic dermatitis (AD) is a chronic, systemic, inflammatory disease that affects the skin and is
characterized by persistent itch and marked redness. AD is associated with an increased …