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New developments in RiPP discovery, enzymology and engineering
Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …
Bacillus velezensis FZB42 in 2018: The Gram-Positive Model Strain for Plant Growth Promotion and Biocontrol
Bacillus velezensis FZB42, the model strain for Gram-positive plant-growth-promoting and
biocontrol rhizobacteria, has been isolated in 1998 and sequenced in 2007. In order to …
biocontrol rhizobacteria, has been isolated in 1998 and sequenced in 2007. In order to …
antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline
K Blin, S Shaw, K Steinke, R Villebro… - Nucleic acids …, 2019 - academic.oup.com
Secondary metabolites produced by bacteria and fungi are an important source of
antimicrobials and other bioactive compounds. In recent years, genome mining has seen …
antimicrobials and other bioactive compounds. In recent years, genome mining has seen …
antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification
Many antibiotics, chemotherapeutics, crop protection agents and food preservatives
originate from molecules produced by bacteria, fungi or plants. In recent years, genome …
originate from molecules produced by bacteria, fungi or plants. In recent years, genome …
A new genome-mining tool redefines the lasso peptide biosynthetic landscape
Ribosomally synthesized and post-translationally modified peptide (RiPP) natural products
are attractive for genome-driven discovery and re-engineering, but limitations in …
are attractive for genome-driven discovery and re-engineering, but limitations in …
The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes
Microorganisms produce natural products that are frequently used in the development of
antibacterial, antiviral, and anticancer drugs, pesticides, herbicides, or fungicides. In recent …
antibacterial, antiviral, and anticancer drugs, pesticides, herbicides, or fungicides. In recent …
Secondary metabolite production and the safety of industrially important members of the Bacillus subtilis group
CR Harwood, JM Mouillon, S Pohl… - FEMS microbiology …, 2018 - academic.oup.com
Members of the 'Bacillus subtilis group'include some of the most commercially important
bacteria, used for the production of a wide range of industrial enzymes and fine …
bacteria, used for the production of a wide range of industrial enzymes and fine …
The antiSMASH database version 4: additional genomes and BGCs, new sequence-based searches and more
Many microorganisms produce natural products that are frequently used in the development
of medicines and crop protection agents. Genome mining has evolved into a prominent …
of medicines and crop protection agents. Genome mining has evolved into a prominent …
The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
Natural products originating from microorganisms are frequently used in antimicrobial and
anticancer drugs, pesticides, herbicides or fungicides. In the last years, the increasing …
anticancer drugs, pesticides, herbicides or fungicides. In the last years, the increasing …
Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome
Plants are colonized by phylogenetically diverse microorganisms that affect plant growth
and health. Representative genome-sequenced culture collections of bacterial isolates from …
and health. Representative genome-sequenced culture collections of bacterial isolates from …