Despite the ability to characterize the plasticity of powders in a material-sparing and
expedited manner, the in-die Heckel analysis has been widely criticized for its sensitivity to …

Mechanical properties of pharmaceutical materials, eg, Young's modulus (E), indentation
hardness (H), and tensile strength (σ t), play an important role in powder compaction …

As an essential formulation component for large-scale tablet manufacturing, the lubricant
preserves tooling by reducing die-wall friction. Unfortunately, lubrication also often results in …

Clear understanding of the relationships among crystal structure, mechanical properties,
and tableting performance is of enormous importance for successful development of tablet …

A discrete numerical analysis of the yield and damage properties associated with a cohesive
granular system composed of ductile particles is hereby presented. Such a modelling …

An equation describing tablet tensile strength as a function of compaction pressure was
derived from the Ryshkewitch and Kuentz-Leuenberger equations. The equation was used …

Fast disintegrating tablets have commonly been used for fast oral drug delivery to patients
with swallowing difficulties. The different characteristics of the pore structure of such …