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Long terminal repeats: from parasitic elements to building blocks of the transcriptional regulatory repertoire
The life cycle of endogenous retroviruses (ERVs), also called long terminal repeat (LTR)
retrotransposons, begins with transcription by RNA polymerase II followed by reverse …
retrotransposons, begins with transcription by RNA polymerase II followed by reverse …
Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis
A number of observations have led researchers to postulate that, despite being replication‐
defective, human endogenous retroviruses (HERVs) may have retained the potential to …
defective, human endogenous retroviruses (HERVs) may have retained the potential to …
TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells
TRIM28 is a corepressor that mediates transcriptional silencing by establishing local
heterochromatin. Here, we show that deletion of TRIM28 in neural progenitor cells (NPCs) …
heterochromatin. Here, we show that deletion of TRIM28 in neural progenitor cells (NPCs) …
[HTML][HTML] COVID-19 in children: expressions of type I/II/III interferons, TRIM28, SETDB1, and endogenous retroviruses in mild and severe cases
PA Tovo, S Garazzino, V Dapra, G Pruccoli… - International Journal of …, 2021 - mdpi.com
Children with the new coronavirus disease 2019 (COVID-19) have milder symptoms and a
better prognosis than adult patients. Several investigations assessed type I, II, and III …
better prognosis than adult patients. Several investigations assessed type I, II, and III …
Endogenous florendoviruses are major components of plant genomes and hallmarks of virus evolution
The extent and importance of endogenous viral elements have been extensively described
in animals but are much less well understood in plants. Here we describe a new genus of …
in animals but are much less well understood in plants. Here we describe a new genus of …
Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes
Abstract Background Human endogenous retroviruses (HERVs) are ancient sequences
integrated in the germ line cells and vertically transmitted through the offspring constituting …
integrated in the germ line cells and vertically transmitted through the offspring constituting …
Evolution of endogenous retroviruses in the subfamily of caprinae
The interest in endogenous retroviruses (ERVs) has been fueled by their impact on the
evolution of the host genome. In this study, we used multiple pipelines to conduct a de novo …
evolution of the host genome. In this study, we used multiple pipelines to conduct a de novo …
[HTML][HTML] Enhanced transcription of human endogenous retroviruses and TRIM28 downregulation in patients with inflammatory bowel disease
Inflammatory bowel disease (IBD) includes patients affected by Crohn's disease or
ulcerative colitis. IBD is thought to be a chronic immune-mediated disease, but its origin …
ulcerative colitis. IBD is thought to be a chronic immune-mediated disease, but its origin …
Identification and characterisation of endogenous Avian Leukosis Virus subgroup E (ALVE) insertions in chicken whole genome sequencing data
Abstract Background Endogenous retroviruses (ERVs) are the remnants of retroviral
infections which can elicit prolonged genomic and immunological stress on their host …
infections which can elicit prolonged genomic and immunological stress on their host …
Endogenous retroviruses transcriptional modulation after severe infection, trauma and burn
O Tabone, M Mommert, C Jourdan, E Cerrato… - Frontiers in …, 2019 - frontiersin.org
Although human endogenous retroviruses (HERVs) expression is a growing subject of
interest, no study focused before on specific endogenous retroviruses loci activation in …
interest, no study focused before on specific endogenous retroviruses loci activation in …