Molecular tools and analytical approaches for the characterization of farm animal genetic diversity

JA Lenstra, LF Groeneveld, H Eding… - Animal …, 2012 - Wiley Online Library
Genetic studies of livestock populations focus on questions of domestication, within‐and
among‐breed diversity, breed history and adaptive variation. In this review, we describe the …

Copy number variation in the genomes of domestic animals

A Clop, O Vidal, M Amills - Animal genetics, 2012 - Wiley Online Library
Copy number variation (CNV) might be one of the main contributors to phenotypic diversity
and evolutionary adaptation in animals and plants, employing a wide variety of mechanisms …

Multiple genomic signatures of selection in goats and sheep indigenous to a hot arid environment

ES Kim, AR Elbeltagy, AM Aboul-Naga, B Rischkowsky… - Heredity, 2016 - nature.com
Goats and sheep are versatile domesticates that have been integrated into diverse
environments and production systems. Natural and artificial selection have shaped the …

Copy number variation of individual cattle genomes using next-generation sequencing

DM Bickhart, Y Hou, SG Schroeder, C Alkan… - Genome …, 2012 - genome.cshlp.org
Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in
or near segmental duplication regions are often intractable. Using a read depth approach …

Genomic characteristics of cattle copy number variations

Y Hou, GE Liu, DM Bickhart, MF Cardone, K Wang… - BMC genomics, 2011 - Springer
Background Copy number variation (CNV) represents another important source of genetic
variation complementary to single nucleotide polymorphism (SNP). High-density SNP array …

The challenges and importance of structural variation detection in livestock

DM Bickhart, GE Liu - Frontiers in genetics, 2014 - frontiersin.org
Recent studies in humans and other model organisms have demonstrated that structural
variants (SVs) comprise a substantial proportion of variation among individuals of each …

Identification of copy number variation in Tibetan sheep using whole genome resequencing reveals evidence of genomic selection

H Shi, T Li, M Su, H Wang, Q Li, X Lang, Y Ma - BMC genomics, 2023 - Springer
Background Copy number variation (CNV) is an important source of structural variation in
the mammalian genome. CNV assays present a new method to explore the genomic …

Genome-wide detection of CNVs in Chinese indigenous sheep with different types of tails using ovine high-density 600K SNP arrays

C Zhu, H Fan, Z Yuan, S Hu, X Ma, J Xuan, H Wang… - Scientific reports, 2016 - nature.com
Chinese indigenous sheep can be classified into three types based on tail morphology: fat-
tailed, fat-rumped, and thin-tailed sheep, of which the typical breeds are large-tailed Han …

Analysis of copy number variations in the sheep genome using 50K SNP BeadChip array

J Liu, L Zhang, L Xu, H Ren, J Lu, X Zhang, S Zhang… - BMC genomics, 2013 - Springer
Background In recent years, genome-wide association studies have successfully uncovered
single-nucleotide polymorphisms (SNPs) associated with complex traits such as diseases …

CNV discovery for milk composition traits in dairy cattle using whole genome resequencing

Y Gao, J Jiang, S Yang, Y Hou, GE Liu, S Zhang… - BMC genomics, 2017 - Springer
Abstract Background Copy number variations (CNVs) are important and widely distributed in
the genome. CNV detection opens a new avenue for exploring genes associated with …