All wrapped up: stabilization of enzymes within single enzyme nanoparticles

R Chapman, MH Stenzel - Journal of the American Chemical …, 2019 - ACS Publications
Enzymes are extremely useful in many industrial and pharmaceutical areas due to their
ability to catalyze reactions with high selectivity. In order to extend their lifetime, significant …

What do we learn from enzyme behaviors in organic solvents?–Structural functionalization of ionic liquids for enzyme activation and stabilization

H Zhao - Biotechnology Advances, 2020 - Elsevier
Enzyme activity in nonaqueous media (eg conventional organic solvents) is typically lower
than in water by several orders of magnitude. There is a rising interest of develo** new …

On complex coacervate core micelles: Structure-function perspectives

JR Magana, CCM Sproncken, IK Voets - Polymers, 2020 - mdpi.com
The co-assembly of ionic-neutral block copolymers with oppositely charged species
produces nanometric colloidal complexes, known, among other names, as complex …

Glucose Oxidase-Loaded MnFe2O4 Nanoparticles for Hyperthermia and Cancer Starvation Therapy

M Anithkumar, A Rajan S, A Khan… - ACS Applied Nano …, 2023 - ACS Publications
Nanoparticle-mediated starvation therapy is a promising therapeutic approach for cancer
treatment. Here, we report a novel therapeutic nanosystem (GOx@ PEG-MnFe2O4) …

Solubilizing and stabilizing proteins in anhydrous ionic liquids through formation of protein–polymer surfactant nanoconstructs

APS Brogan, JP Hallett - Journal of the American Chemical …, 2016 - ACS Publications
Nonaqueous biocatalysis is rapidly becoming a desirable tool for chemical and fuel
synthesis in both the laboratory and industry. Similarly, ionic liquids are increasingly popular …

Exudate Unidirectional Pump to Promote Glucose Catabolism Triggering Fenton‐Like Reaction for Chronic Diabetic Wounds Therapy

Y Liang, W Wang, K Qi, Y Wei, W Zhao, H **e… - Advanced …, 2024 - Wiley Online Library
The massive accumulation of exudate containing high concentrations of glucose causes
wound infection and triggers the release of inflammatory factors, which in turn delays the …

Liquefaction of biopolymers: solvent-free liquids and liquid crystals from nucleic acids and proteins

K Liu, C Ma, R Göstl, L Zhang… - Accounts of Chemical …, 2017 - ACS Publications
Conspectus Biomacromolecules, such as nucleic acids, proteins, and virus particles, are
persistent molecular entities with dimensions that exceed the range of their intermolecular …

Creation of stable water-free antibody based protein liquids

JM Slocik, PB Dennis, Z Kuang, A Pelton… - Communications …, 2021 - nature.com
Antibodies represent highly specific and high binding affinity biomolecular recognition
elements for diagnostic assays, biosensors, and therapeutics, but are sensitive to …

Polyion complex-templated synthesis of cross-linked single-enzyme nanoparticles

Y Wang, YT Cheng, C Cao, JD Oliver… - …, 2020 - ACS Publications
Single-enzyme nanoparticles (SENs), which encapsulate individual enzymes in a thin
polymer network, offer exciting possibilities for stabilizing enzymes and tuning their activity …

Three-dimensional printable enzymatically active plastics

WH Zhang, GJ Day, I Zampetakis… - ACS Applied Polymer …, 2021 - ACS Publications
Here, we describe a facile route to the synthesis of enzymatically active highly fabricable
plastics, where the enzyme is an intrinsic component of the material. This is facilitated by the …