Anticancer activities of Nigella sativa (black cumin)

A Khan, HC Chen, M Tania, DZ Zhang - African Journal of Traditional …, 2011 - ajol.info
Nigella sativa has been used as traditional medicine for centuries. The crude oil and
thymoquinone (TQ) extracted from its seeds and oil are effective against many diseases like …

Involvement of cytochrome P450 in reactive oxygen species formation and cancer

EG Hrycay, SM Bandiera - Advances in Pharmacology, 2015 - Elsevier
This review examines the involvement of cytochrome P450 (CYP) enzymes in the formation
of reactive oxygen species in biological systems and discusses the possible involvement of …

Protective effect of Nigella sativa oil against tramadol-induced tolerance and dependence in mice: role of nitric oxide and oxidative stress

AO Abdel-Zaher, MS Abdel-Rahman, FM ELwasei - Neurotoxicology, 2011 - Elsevier
Nigella sativa seed extracts and its oil have been exploited for their various health benefits.
In this study, the effects of N. sativa oil on tramadol-induced tolerance and dependence and …

The effect of Nigella sativa Linn. seed on memory, attention and cognition in healthy human volunteers

MSB Sayeed, M Asaduzzaman, H Morshed… - Journal of …, 2013 - Elsevier
Background Experimental evidences have demonstrated that Nigella sativa Linn. seed (NS)
has positive modulation effects on aged rats with memory impairments, prevents against …

Pequi (Caryocar brasiliense Camb.) almond oil attenuates carbon tetrachloride-induced acute hepatic injury in rats: Antioxidant and anti-inflammatory effects

LRO Torres, FC de Santana, FL Torres-Leal… - Food and Chemical …, 2016 - Elsevier
Carbon tetrachloride (CCl 4) is a potent hepatotoxin, capable of generating free radicals that
lead to oxidative stress and the inflammation process. Pequi almond oil (PAO) has been …

Radiation-modifying abilities of Nigella sativa and thymoquinone on radiation-induced nitrosative stress in the brain tissue

A Ahlatci, A Kuzhan, S Taysi, OC Demirtas, HE Alkis… - Phytomedicine, 2014 - Elsevier
To investigate Nigella sativa oil (NSO) and Thymoquinone (TQ) for their antioxidant effects
on the brain tissue of rats exposed to ionizing radiation. Fifty-four male albino Wistar rats …

Studying the inhibitory effect of quercetin and thymoquinone on human cytochrome P450 enzyme activities

F Elbarbry, A Ung, K Abdelkawy - Pharmacognosy magazine, 2018 - pmc.ncbi.nlm.nih.gov
Background: Quercetin (QR) and thymoquinone (TQ) are herbal remedies that are currently
extensively used by the general population to prevent and treat various chronic conditions …

[HTML][HTML] Liver injury by carbon tetrachloride intoxication in 16 patients treated with forced ventilation to accelerate toxin removal via the lungs: A clinical report

R Teschke - Toxics, 2018 - mdpi.com
Carbon tetrachloride (CCl4) is an efficient but highly toxic solvent, used in households and
commercially in the industry under regulatory surveillance to ensure safety at the working …

[PDF][PDF] Black Seed (Nigella sativa) as antimicrobial drug: a mini-review

EM Abdallah - Novel Approches in Drug Designing and Develop, 2017 - researchgate.net
In the last decades, the antibiotics-resistance phenomenon has become a global health
crisis, due to the rapid emergence of multi-drug resistant pathogens. Novel approaches in …

Blockade of Nitric Oxide Overproduction and Oxidative Stress by Nigella sativa Oil Attenuates Morphine-Induced Tolerance and Dependence in Mice

AO Abdel-Zaher, MS Abdel-Rahman… - Neurochemical …, 2010 - Springer
The effects of Nigella sativa oil on morphine-induced tolerance and dependence in mice
and possible mechanism (s) of these effects were investigated, for the first time, in this study …