B cells, antibodies, and more
B cells play a central role in the immunopathogenesis of glomerulonephritides and
transplant rejection. B cells secrete antibodies that contribute to tissue injury via multiple …
transplant rejection. B cells secrete antibodies that contribute to tissue injury via multiple …
Remembrance of things past: long-term B cell memory after infection and vaccination
AKE Palm, C Henry - Frontiers in immunology, 2019 - frontiersin.org
The success of vaccines is dependent on the generation and maintenance of immunological
memory. The immune system can remember previously encountered pathogens, and …
memory. The immune system can remember previously encountered pathogens, and …
Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes
A Cerutti, M Cols, I Puga - Nature Reviews Immunology, 2013 - nature.com
Protective responses to microorganisms involve the nonspecific but rapid defence
mechanisms of the innate immune system, followed by the specific but slow defence …
mechanisms of the innate immune system, followed by the specific but slow defence …
Vaccine technologies and platforms for infectious diseases: Current progress, challenges, and opportunities
Vaccination is a key component of public health policy with demonstrated cost-effective
benefits in protecting both human and animal populations. Vaccines can be manufactured …
benefits in protecting both human and animal populations. Vaccines can be manufactured …
BAFF and BAFF-receptor in B cell selection and survival
The BAFF-receptor (BAFFR) is encoded by the TNFRSF13C gene and is one of the main pro-
survival receptors in B cells. Its function is impressively documented in humans by a …
survival receptors in B cells. Its function is impressively documented in humans by a …
Neonatal adaptive immunity comes of age
B Adkins, C Leclerc, S Marshall-Clarke - Nature Reviews Immunology, 2004 - nature.com
The past decade has brought great strides in our understanding of adaptive immunity in
neonatal mice. Although poor immune responses are commonly observed, it is now clear …
neonatal mice. Although poor immune responses are commonly observed, it is now clear …
Post-splenectomy and hyposplenic states
A Di Sabatino, R Carsetti, GR Corazza - The Lancet, 2011 - thelancet.com
The spleen is crucial in regulating immune homoeostasis through its ability to link innate and
adaptive immunity and in protecting against infections. The impairment of splenic function is …
adaptive immunity and in protecting against infections. The impairment of splenic function is …
Effector and regulatory B cells: modulators of CD4+ T cell immunity
FE Lund, TD Randall - Nature Reviews Immunology, 2010 - nature.com
B cells are essential for humoral immunity, but the role that they have in regulating CD4+ T
cell responses remains controversial. However, new data showing that the transient …
cell responses remains controversial. However, new data showing that the transient …
Human blood IgM “memory” B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire
S Weller, MC Braun, BK Tan, A Rosenwald, C Cordier… - Blood, 2004 - ashpublications.org
The human peripheral B-cell compartment displays a large population of immunoglobulin M–
positive, immunoglobulin D–positive CD27+ (IgM+ IgD+ CD27+)“memory” B cells carrying a …
positive, immunoglobulin D–positive CD27+ (IgM+ IgD+ CD27+)“memory” B cells carrying a …
Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM+ Memory B Cells
Background The hemagglutinin (HA) glycoprotein is the principal target of protective
humoral immune responses to influenza virus infections but such antibody responses only …
humoral immune responses to influenza virus infections but such antibody responses only …