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Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …
disease worldwide and is strongly associated with the presence of oxidative stress …
[HTML][HTML] Effects of high fat diets on rodent liver bioenergetics and oxidative imbalance
Human metabolic diseases can be mimicked in rodents by using dietary interventions such
as high fat diets (HFD). Nonalcoholic fatty liver disease (NAFLD) develops as a result of HFD …
as high fat diets (HFD). Nonalcoholic fatty liver disease (NAFLD) develops as a result of HFD …
Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease
Z Kurt, R Barrere-Cain, J LaGuardia… - Biology of sex …, 2018 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) encompasses benign steatosis and
more severe conditions such as non-alcoholic steatohepatitis (NASH), cirrhosis, and liver …
more severe conditions such as non-alcoholic steatohepatitis (NASH), cirrhosis, and liver …
Long‐term measures of dyslipidemia, inflammation, and oxidative stress in rats fed a high‐fat/high‐fructose diet
C Feillet‐Coudray, G Fouret, C Vigor, B Bonafos… - Lipids, 2019 - Wiley Online Library
Inflammation and oxidative stress are thought to be involved in, or associated with, the
development of obesity, dyslipidemia, hepatic steatosis, and insulin resistance. This work …
development of obesity, dyslipidemia, hepatic steatosis, and insulin resistance. This work …
Mitochondrial dysfunction in nonalcoholic steatohepatitis
The pathogenesis of nonalcoholic steatohepatitis (NASH) is poorly understood and the
mechanisms are still being elucidated. Mitochondrial dysfunction participates at different …
mechanisms are still being elucidated. Mitochondrial dysfunction participates at different …
Diet-sensitive sources of reactive oxygen species in liver mitochondria: role of very long chain acyl-CoA dehydrogenases
High fat diets and accompanying hepatic steatosis are highly prevalent conditions. Previous
work has shown that steatosis is accompanied by enhanced generation of reactive oxygen …
work has shown that steatosis is accompanied by enhanced generation of reactive oxygen …
Exploiting common aspects of obesity and Alzheimer's disease
Alzheimer's disease (AD) is an example of age-related dementia, and there are still no
known preventive or curative measures for this disease. Obesity and associated metabolic …
known preventive or curative measures for this disease. Obesity and associated metabolic …
A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes
I Grattagliano, CV Diogo… - World journal of …, 2013 - pmc.ncbi.nlm.nih.gov
AIM: To investigate the effectiveness of antioxidant compounds in modulating mitochondrial
oxidative alterations and lipids accumulation in fatty hepatocytes. METHODS: Silybin …
oxidative alterations and lipids accumulation in fatty hepatocytes. METHODS: Silybin …
NF‐κB‐upregulated miR‐155‐5p promotes hepatocyte mitochondrial dysfunction to accelerate the development of nonalcoholic fatty liver disease through …
M Shen, H Pan, J Ke, F Zhao - Journal of Biochemical and …, 2022 - Wiley Online Library
Previous studies have highlighted the involvement of nuclear factor kappa B (NF‐κB) in the
development of nonalcoholic fatty liver disease (NAFLD). The purpose of our investigation is …
development of nonalcoholic fatty liver disease (NAFLD). The purpose of our investigation is …
[HTML][HTML] Wilson disease: At the crossroads between genetics and epigenetics—A review of the evidence
DA Kieffer, V Medici - Liver research, 2017 - Elsevier
Environmental factors, including diet, exercise, stress, and toxins, profoundly impact disease
phenotypes. This review examines how Wilson disease (WD), an autosomal recessive …
phenotypes. This review examines how Wilson disease (WD), an autosomal recessive …