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Multitalented synthetic antimicrobial peptides and their antibacterial, antifungal and antiviral mechanisms
Despite the great strides in healthcare during the last century, some challenges still
remained unanswered. The development of multi-drug resistant bacteria, the alarming …
remained unanswered. The development of multi-drug resistant bacteria, the alarming …
Theranostics and artificial intelligence: new frontiers in personalized medicine
The field of theranostics is rapidly advancing, driven by the goals of enhancing patient care.
Recent breakthroughs in artificial intelligence (AI) and its innovative theranostic applications …
Recent breakthroughs in artificial intelligence (AI) and its innovative theranostic applications …
Peptide-based drug delivery systems
Peptide-based drug delivery systems have many advantages when compared to synthetic
systems in that they have better biocompatibility, biochemical and biophysical properties …
systems in that they have better biocompatibility, biochemical and biophysical properties …
Peptides as pharmacological carriers to the brain: promises, shortcomings and challenges
Central nervous system (CNS) diseases are among the most difficult to treat, mainly
because the vast majority of the drugs fail to cross the blood-brain barrier (BBB) or to reach …
because the vast majority of the drugs fail to cross the blood-brain barrier (BBB) or to reach …
Targeted nanomedicine: Lessons learned and future directions
N Veiga, Y Diesendruck, D Peer - Journal of Controlled Release, 2023 - Elsevier
Designing a therapeutic modality that will reach a certain organ, tissue, or cell type is crucial
for both the therapeutic efficiency and to limit off-target adverse effects. Nanoparticles …
for both the therapeutic efficiency and to limit off-target adverse effects. Nanoparticles …
[HTML][HTML] The chemical scaffold of theranostic radiopharmaceuticals: radionuclide, bifunctional chelator, and pharmacokinetics modifying linker
Therapeutic radiopharmaceuticals have been researched extensively in the last decade as
a result of the growing research interest in personalized medicine to improve diagnostic …
a result of the growing research interest in personalized medicine to improve diagnostic …
[PDF][PDF] Engineering lanthipeptides by introducing a large variety of RiPP modifications to obtain new-to-nature bioactive peptides
Y Fu, Y Xu, F Ruijne, OP Kuipers - FEMS Microbiology Reviews, 2023 - academic.oup.com
Natural bioactive peptide discovery is a challenging and time-consuming process. However,
advances in synthetic biology are providing promising new avenues in peptide engineering …
advances in synthetic biology are providing promising new avenues in peptide engineering …
Non-canonical amino acids as building blocks for peptidomimetics: structure, function, and applications
This review provides a fresh overview of non-canonical amino acids and their applications in
the design of peptidomimetics. Non-canonical amino acids appear widely distributed in …
the design of peptidomimetics. Non-canonical amino acids appear widely distributed in …
[HTML][HTML] Recent applications of retro-inverso peptides
Natural and de novo designed peptides are gaining an ever-growing interest as drugs
against several diseases. Their use is however limited by the intrinsic low bioavailability and …
against several diseases. Their use is however limited by the intrinsic low bioavailability and …
Antimicrobial peptides as antimicrobials for wound care management: A comprehensive review
Antimicrobial peptides (AMPs) are low-molecular-weight proteins having a presence in
almost all organisms, from prokaryotes to eukaryotes, and have been a fundamental part of …
almost all organisms, from prokaryotes to eukaryotes, and have been a fundamental part of …