[HTML][HTML] Resting-state connectivity in neurodegenerative disorders: Is there potential for an imaging biomarker?

C Hohenfeld, CJ Werner, K Reetz - NeuroImage: Clinical, 2018 - Elsevier
Biomarkers in whichever modality are tremendously important in diagnosing of disease,
tracking disease progression and clinical trials. This applies in particular for disorders with a …

Aberrant spontaneous low-frequency brain activity in amnestic mild cognitive impairment: a meta-analysis of resting-state fMRI studies

PL Pan, L Zhu, TT Yu, HC Shi, B Zhang, R Qin… - Ageing research …, 2017 - Elsevier
Recent resting-state functional magnetic resonance imaging (rs-fMRI) studies have provided
strong evidence of abnormal spontaneous brain activity in amnestic mild cognitive …

Altered directed functional connectivity of the hippocampus in mild cognitive impairment and Alzheimer's disease: a resting-state fMRI study

J Xue, H Guo, Y Gao, X Wang, H Cui, Z Chen… - Frontiers in aging …, 2019 - frontiersin.org
The hippocampus is generally reported as one of the regions most impacted by Alzheimer's
disease (AD) and is closely associated with memory function and orientation. Undirected …

Medial temporal lobe disconnection and hyperexcitability across Alzheimer's disease stages

L Pasquini, F Rahmani… - Journal of …, 2019 - journals.sagepub.com
The posteromedial cortex (PMC) and medial temporal lobes (MTL) are two brain regions
particularly vulnerable in Alzheimer's disease (AD). We have reviewed the spatiotemporal …

Default mode network functional connectivity in early and late mild cognitive impairment: results from the Alzheimer's disease neuroimaging initiative

ES Lee, K Yoo, YB Lee, J Chung, JE Lim… - Alzheimer Disease & …, 2016 - journals.lww.com
Background: Default mode network (DMN) functional connectivity is one of the
neuroimaging candidate biomarkers of Alzheimer disease. However, no studies have …

Complexity in neuropsychological assessments of cognitive impairment: A network analysis approach

G Tosi, C Borsani, S Castiglioni, R Daini, M Franceschi… - Cortex, 2020 - Elsevier
In a neuropsychological assessment, each test aims at measuring a single cognitive
function. However, test performance depends on an interconnected system of cognitive …

The effects of transcutaneous vagus nerve stimulation on functional connectivity within semantic and hippocampal networks in mild cognitive impairment

AJ Murphy, AG O'Neal, RA Cohen, DG Lamb… - …, 2023 - Springer
Better treatments are needed to improve cognition and brain health in people with mild
cognitive impairment (MCI) and Alzheimer's disease (AD). Transcutaneous vagus nerve …

[HTML][HTML] The effect of beta-amyloid and tau protein aggregations on magnetic susceptibility of anterior hippocampal laminae in Alzheimer's diseases

Z Zhao, L Zhang, Q Wen, W Luo, W Zheng, T Liu… - NeuroImage, 2021 - Elsevier
Previous studies have reported the changes of magnetic susceptibility induced by iron
deposition in hippocampus of Alzheimer's disease (AD) brains. It is well-known that …

A network flow-based analysis of cognitive reserve in normal ageing and Alzheimer's disease

S Wook Yoo, CE Han, JS Shin, S Won Seo, DL Na… - Scientific reports, 2015 - nature.com
Cognitive reserve is the ability to sustain cognitive function even with a certain amount of
brain damages. Here we investigate the neural compensation mechanism of cognitive …

Crosstalk between depression and dementia with resting-state fMRI studies and its relationship with cognitive functioning

J Kim, YK Kim - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common type of dementia, and depression is a risk
factor for develo** AD. Epidemiological studies provide a clinical correlation between late …