The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …

Childhood socio-economic status (SES), a measure of the availability of material and social
resources, is one of the strongest predictors of lifelong well-being. Here we review evidence …

Neurobiological abnormalities associated with psychiatric disorders do not map well to
existing diagnostic categories. High co-morbidity suggests dimensional circuit-level …

The 21st century marks the emergence of “big data” with a rapid increase in the availability
of datasets with multiple measurements. In neuroscience, brain-imaging datasets are more …

A central goal in neuroscience is to determine how the brain's neuronal circuits generate
perception, cognition and emotions and how these lead to appropriate behavioural actions …

Some brain regions have a central role in supporting integrated brain function, marking them
as network hubs. Given the functional importance of hubs, it is natural to ask how they …

Studies comparing diverse groups have shown that many psychiatric diseases involve
disruptions across distributed large-scale networks of the brain. There is hope that functional …

Like other classes of treatments described in this issue's section, neuroactive steroids have
been studied for decades but have risen as a new class of rapid-acting, durable …

In recent years, there has been an increase in applications of network science in many
different fields. In clinical neuroscience and psychopathology, the developments and …

Highlights•Resting-state fMRI biomarkers in psychiatry often lack disorder specificity.•
Transdiagnostic study designs allow direct assessment of biomarker specificity.•p-factor …