A review and database of snake venom proteomes

T Tasoulis, GK Isbister - Toxins, 2017 - mdpi.com
Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in …

Multifunctional toxins in snake venoms and therapeutic implications: from pain to hemorrhage and necrosis

CR Ferraz, A Arrahman, C **e, NR Casewell… - Frontiers in ecology …, 2019 - frontiersin.org
Animal venoms have evolved over millions of years for prey capture and defense from
predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides …

Venomics: integrative venom proteomics and beyond

JJ Calvete - Biochemical Journal, 2017 - portlandpress.com
Venoms are integrated phenotypes that evolved independently in, and are used for
predatory and defensive purposes by, a wide phylogenetic range of organisms. The same …

The search for natural and synthetic inhibitors that would complement antivenoms as therapeutics for snakebite envenoming

JM Gutiérrez, LO Albulescu, RH Clare, NR Casewell… - Toxins, 2021 - mdpi.com
A global strategy, under the coordination of the World Health Organization, is being unfolded
to reduce the impact of snakebite envenoming. One of the pillars of this strategy is to ensure …

Medicinal plants for the treatment of local tissue damage induced by snake venoms: an overview from traditional use to pharmacological evidence

J Félix-Silva, AA Silva-Junior… - Evidence‐Based …, 2017 - Wiley Online Library
Snakebites are a serious problem in public health due to their high morbimortality. Most of
snake venoms produce intense local tissue damage, which could lead to temporary or …

From fangs to pharmacology: the future of snakebite envenoming therapy

AH Laustsen, M Engmark, C Milbo… - Current …, 2016 - ingentaconnect.com
The snake is the symbol of medicine due to its association with Asclepius, the Greek God of
medicine, and so with good reasons. More than 725 species of venomous snakes have …

Next-generation snake venomics: protein-locus resolution through venom proteome decomplexation

JJ Calvete - Expert review of proteomics, 2014 - Taylor & Francis
Venom research has been continuously enhanced by technological advances. High-
throughput technologies are changing the classical paradigm of hypothesis-driven research …

Comparative venomics of the Prairie Rattlesnake (Crotalus viridis viridis) from Colorado: Identification of a novel pattern of ontogenetic changes in venom composition …

AJ Saviola, D Pla, L Sanz, TA Castoe, JJ Calvete… - Journal of …, 2015 - Elsevier
Here we describe and compare the venomic and antivenomic characteristics of both
neonate and adult Prairie Rattlesnake (Crotalus viridis viridis) venoms. Although both …

[HTML][HTML] Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance

JJ Calvete, B Lomonte, AJ Saviola, F Bonilla, M Sasa… - Toxicon: X, 2021 - Elsevier
Snakebite envenoming is a neglected tropical disease that may claim over 100,000 human
lives annually worldwide. Snakebite occurs as the result of an interaction between a human …

Proteomic characterization and comparison of venoms from two elapid snakes (Bungarus multicinctus and Naja atra) from China

LL Shan, JF Gao, YX Zhang, SS Shen, Y He, J Wang… - Journal of …, 2016 - Elsevier
Bungarus multicinctus (many-banded krait) and Naja atra (Chinese cobra) are widely
distributed and medically important venomous snakes in China; however, their venom …