Natural products, and especially the active ingredients found in traditional Chinese medicine
(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in …

Ferroptosis, first proposed in 2012, is an iron-dependent form of regulated cell death
characterized by excessive polyunsaturated fatty acid oxidation. In the past decade …

Parabacteroides distasonis (P. distasonis) plays an important role in human health,
including diabetes, colorectal cancer and inflammatory bowel disease. Here, we show that …

Abstract Background Approximately 8–9% of the world's population is affected by
autoimmune diseases, and yet the mechanism of autoimmunity trigger is largely …

Colorectal cancer (CRC) is the third most common cause of cancer mortality worldwide.
Approximately 40% of CRC patients are KRAS sequence variation, including KRAS G13D …

The liver can succumb to oxidant damage during the development of chronic liver diseases.
Despite their physiological relevance to hepatic homeostasis, excessive reactive …

Tumour cells often display an active metabolic profile, leading to the intracellular
accumulation of reactive oxygen species. As a member of the peroxidase family …

The emergence and rapid spread of methicillin‐resistant Staphylococcus aureus (MRSA)
raise a critical need for alternative therapeutic options. New antibacterial drugs and targets …

Ferroptosis is an iron-dependent form of programmed cell death driven by excessive
oxidation of polyunsaturated phospholipids on cellular membranes. Accumulating evidence …

Diabetes mellitus (DM) and its complications are major diseases that affect human health
and pose a serious threat to global public health. Although the prevention and treatment of …