Medical applications of porous biomaterials: features of porosity and tissue‐specific implications for biocompatibility

JL Hernandez, KA Woodrow - Advanced healthcare materials, 2022 - Wiley Online Library
Porosity is an important material feature commonly employed in implants and tissue
scaffolds. The presence of material voids permits the infiltration of cells, mechanical …

Bioinspired nanotopographical design of drug delivery systems

JA Finbloom, C Huynh, X Huang… - Nature Reviews …, 2023 - nature.com
Effective drug delivery is important in the treatment of various biomedical conditions, ranging
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …

Electrospun nanofibers for customized drug-delivery systems

S Kajdič, O Planinšek, M Gašperlin, P Kocbek - Journal of Drug Delivery …, 2019 - Elsevier
Nanofiber-based drug-delivery systems are widely applicable for specific drug release,
according to the target location and timing, to achieve the desired therapeutic effects. A …

Advanced materials for drug delivery across mucosal barriers

SP Bandi, S Bhatnagar, VVK Venuganti - Acta biomaterialia, 2021 - Elsevier
Mucus is a viscoelastic gel that traps pathogens and other foreign particles to limit their
penetration into the underlying epithelium. Dosage forms containing particle-based drug …

Untangling mucosal drug delivery: engineering, designing, and testing nanoparticles to overcome the mucus barrier

J Watchorn, AJ Clasky, G Prakash… - ACS Biomaterials …, 2022 - ACS Publications
Mucus is a complex viscoelastic gel and acts as a barrier covering much of the soft tissue in
the human body. High vascularization and accessibility have motivated drug delivery to …

Development of electrospun nanofibers that enable high loading and long-term viability of probiotics

K Škrlec, Š Zupančič, SP Mihevc, P Kocbek… - European Journal of …, 2019 - Elsevier
The interest in probiotics has grown in recent years due to increased awareness of the
importance of microbiota for human health. We present the development of monolithic poly …

Delivery technologies for women's health applications

KL Swingle, AS Ricciardi, WH Peranteau… - Nature Reviews …, 2023 - nature.com
The treatment of women's health-related conditions, including reproductive tract and
pregnancy disorders, faces distinct challenges and microenvironments, such as the vaginal …

[HTML][HTML] Effect of tissue microenvironment on fibrous capsule formation to biomaterial-coated implants

JL Hernandez, J Park, S Yao, AK Blakney, HV Nguyen… - Biomaterials, 2021 - Elsevier
Within tissue exposed to the systemic immune system, lymphocytes and fibroblasts act
against biomaterials via the development of a fibrous capsule, known as the foreign body …

Development and characterization of chitosan nanoparticles loaded nanofiber hybrid system for vaginal controlled release of benzydamine

F Tuğcu-Demiröz, S Saar, AA Kara, A Yıldız… - European Journal of …, 2021 - Elsevier
Vaginal infections caused by various pathogens such as fungi, viruses and protozoa are
frequently seen. Systemic and local treatments can be applied to eliminate these infections …

Nanoparticles-in-nanofibers composites: Emphasis on some recent biomedical applications

AM Elsherbini, SA Sabra - Journal of Controlled Release, 2022 - Elsevier
Nanoparticles-in-nanofibers composites comprise an attractive approach for controlling
release and delivery of many active molecules for versatile biomedical applications …