[HTML][HTML] Pharmacological effects and mechanisms of tannic acid

W **g, C **aolan, C Yu, Q Feng, Y Haifeng - Biomedicine & …, 2022 - Elsevier
In recent years, increasing attention has been paid to the pharmacological efficacy of
tannins. Tannic acid (TA), the simplest hydrolysable tannin that has been approved by the …

Role of food-derived antioxidants against cisplatin induced-nephrotoxicity

T Gómez-Sierra, D Eugenio-Pérez… - Food and Chemical …, 2018 - Elsevier
Cancer is a relevant public health problem that represents the second leading cause of
global death. In this regard, cisplatin is a highly effective antineoplastic drug used in …

Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways

AL Alaofi - Frontiers in Pharmacology, 2020 - frontiersin.org
Diabetic neuropathy (DN) is a complicated inauspicious outcome of diabetes, like other
abnormalities of diabetes the cause of DN is still vague and it may be the result of various …

Protective effects of luteolin on diabetic nephropathy in STZ‐induced diabetic rats

GG Wang, XH Lu, W Li, X Zhao… - … and Alternative Medicine, 2011 - Wiley Online Library
Diabetic nephropathy is a long‐term complication of diabetic mellitus. Many experimental
evidences suggest that persistent hyperglycaemia generates intracellular reactive oxygen …

TNF-α, IL-6 and IL-10 expressions, responsible for disparity in action of curcumin against cisplatin-induced nephrotoxicity in rats

P Kumar, K Sulakhiya, CC Barua, N Mundhe - Molecular and cellular …, 2017 - Springer
Cisplatin is a regularly employed effective chemotherapeutic agent for the treatment of many
types of cancer. The main drawback of cisplatin treatment is kidney toxicity which affects 25 …

Momordica charantia polysaccharides mitigate the progression of STZ induced diabetic nephropathy in rats

M Raish, A Ahmad, BL Jan, KM Alkharfy… - International journal of …, 2016 - Elsevier
Diabetic nephropathy (DN) has become a primary cause of end-stage kidney disease.
Several complex dynamics converge together to accelerate the advancement of DN. The …

Tannic acid ameliorates doxorubicin-induced cardiotoxicity and potentiates its anti-cancer activity: potential role of tannins in cancer chemotherapy

K Tikoo, MS Sane, C Gupta - Toxicology and applied pharmacology, 2011 - Elsevier
Doxorubicin, an anthracycline antibiotic, is widely used in the treatment of various solid
tumors including breast cancer. However, its use is limited due to a variety of toxicities …

Change in post‐translational modifications of histone H3, heat‐shock protein‐27 and MAP kinase p38 expression by curcumin in streptozotocin‐induced type I …

K Tikoo, RL Meena, DG Kabra… - British journal of …, 2008 - Wiley Online Library
Background and purpose: Curcumin has been used to treat cancer, diabetes and other
pathologies. However, little is known regarding its role in altering post‐translational …

Methanolic extract of Ephedra alata ameliorates cisplatin-induced nephrotoxicity and hepatotoxicity through reducing oxidative stress and genotoxicity

F Sioud, I Ben Toumia, A Lahmer, R Khlifi… - … Science and Pollution …, 2020 - Springer
Cisplatin (CP) is a powerful anticancer agent used in the treatment of a diverse type of
cancers. Oxidative stress is one of the most important side effects limiting the use of cisplatin …

Cisplatin induced damage in kidney genomic DNA and nephrotoxicity in male rats: the protective effect of grape seed proanthocyanidin extract

AA Saad, MI Youssef, LK El-Shennawy - Food and Chemical Toxicology, 2009 - Elsevier
The clinical use of cisplatin is highly limited, because of its renal toxicity. In this study, the
protective effect of grape seed proanthocyanidin extract (GSPE) against cisplatin-induced …