Multiple factor analysis: principal component analysis for multitable and multiblock data sets
Multiple factor analysis (MFA, also called multiple factorial analysis) is an extension of
principal component analysis (PCA) tailored to handle multiple data tables that measure …
principal component analysis (PCA) tailored to handle multiple data tables that measure …
Positron emission tomography imaging with [18F] flortaucipir and postmortem assessment of Alzheimer disease neuropathologic changes
Importance Positron emission tomography (PET) may increase the diagnostic accuracy and
confirm the underlying neuropathologic changes of Alzheimer disease (AD). Objective To …
confirm the underlying neuropathologic changes of Alzheimer disease (AD). Objective To …
Parallel regulation of memory and emotion supports the suppression of intrusive memories
Intrusive memories often take the form of distressing images that emerge into a person's
awareness, unbidden. A fundamental goal of clinical neuroscience is to understand the …
awareness, unbidden. A fundamental goal of clinical neuroscience is to understand the …
An ExPosition of multivariate analysis with the singular value decomposition in R
ExPosition is a new comprehensive R package providing crisp graphics and implementing
multivariate analysis methods based on the singular value decomposition (svd). The core …
multivariate analysis methods based on the singular value decomposition (svd). The core …
Flortaucipir F 18 quantitation using parametric estimation of reference signal intensity
PET imaging of tau pathology in Alzheimer disease may benefit from the use of white matter
reference regions. These regions have shown reduced variability compared with …
reference regions. These regions have shown reduced variability compared with …
Test–retest reproducibility for the tau PET imaging agent Flortaucipir F 18
MD Devous, AD Joshi, M Navitsky… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Alzheimer disease (AD) is characterized by β-amyloid (Aβ) plaques and tau neurofibrillary
tangles. There are several PET imaging biomarkers for Aβ including 11C-PiB and 18F …
tangles. There are several PET imaging biomarkers for Aβ including 11C-PiB and 18F …
Based on the network degeneration hypothesis: separating individual patients with different neurodegenerative syndromes in a preliminary hybrid PET/MR study
The network degeneration hypothesis (NDH) of neurodegenerative syndromes suggests
that pathologic brain changes distribute primarily along distinct brain networks, which are …
that pathologic brain changes distribute primarily along distinct brain networks, which are …
PET imaging of tau protein targets: a methodology perspective
The two neuropathological hallmarks of Alzheimer's disease (AD) are amyloid-β β plaques
and neurofibrillary tangles of tau protein. Fifteen years ago, Positron Emission Tomography …
and neurofibrillary tangles of tau protein. Fifteen years ago, Positron Emission Tomography …
Adaptive human immunity drives remyelination in a mouse model of demyelination
M El Behi, C Sanson, C Bachelin, L Guillot-Noël… - Brain, 2017 - academic.oup.com
One major challenge in multiple sclerosis is to understand the cellular and molecular
mechanisms leading to disease severity progression. The recently demonstrated correlation …
mechanisms leading to disease severity progression. The recently demonstrated correlation …
Predicting regional tau accumulation with machine learning‐based tau‐PET and advanced radiomics
S Rathore, IA Higgins, J Wang… - … Research & Clinical …, 2024 - Wiley Online Library
INTRODUCTION Alzheimer's disease is partially characterized by the progressive
accumulation of aggregated tau‐containing neurofibrillary tangles. Although the association …
accumulation of aggregated tau‐containing neurofibrillary tangles. Although the association …