The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
E Mogilyansky, I Rigoutsos - Cell Death & Differentiation, 2013 - nature.com
Abstract The miR-17/92 cluster is among the best-studied microRNA clusters. Interest in the
cluster and its members has been increasing steadily and the number of publications has …
cluster and its members has been increasing steadily and the number of publications has …
[HTML][HTML] Differential Pd-nanocrystal facets demonstrate distinct antibacterial activity against Gram-positive and Gram-negative bacteria
Noble metal-based nanomaterials have shown promise as potential enzyme mimetics, but
the facet effect and underlying molecular mechanisms are largely unknown. Herein, with a …
the facet effect and underlying molecular mechanisms are largely unknown. Herein, with a …
[HTML][HTML] Hepatitis B virus and microRNAs: Complex interactions affecting hepatitis B virus replication and hepatitis B virus-associated diseases
J Lamontagne, LF Steel… - World journal of …, 2015 - ncbi.nlm.nih.gov
Chronic infection with the hepatitis B virus (HBV) is the leading risk factor for the
development of hepatocellular carcinoma (HCC). With nearly 750000 deaths yearly …
development of hepatocellular carcinoma (HCC). With nearly 750000 deaths yearly …
miR-CLIP capture of a miRNA targetome uncovers a lincRNA H19–miR-106a interaction
Identifying the interaction partners of noncoding RNAs is essential for elucidating their
functions. We have developed an approach, termed microRNA crosslinking and …
functions. We have developed an approach, termed microRNA crosslinking and …
Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity
AG Telonis, P Loher, Y **g, E Londin… - Nucleic acids …, 2015 - academic.oup.com
Here we describe our study of miRNA isoforms (isomiRs) in breast cancer (BRCA) and
normal breast data sets from the Cancer Genome Atlas (TCGA) repository. We report that the …
normal breast data sets from the Cancer Genome Atlas (TCGA) repository. We report that the …
Graphene-induced pore formation on cell membranes
Examining interactions between nanomaterials and cell membranes can expose underlying
mechanisms of nanomaterial cytotoxicity and guide the design of safer nanomedical …
mechanisms of nanomaterial cytotoxicity and guide the design of safer nanomedical …
Robust Antibacterial Activity of Tungsten Oxide (WO3-x) Nanodots
Antibacterial agents are an important tool in the prevention of bacterial infections. Inorganic
materials are attractive due to their high stability under a variety of conditions compared to …
materials are attractive due to their high stability under a variety of conditions compared to …
MiR-103a-3p targets the 5′ UTR of GPRC5A in pancreatic cells
H Zhou, I Rigoutsos - Rna, 2014 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are short noncoding RNAs that regulate the expression of their targets
in a sequence-dependent manner. For protein-coding transcripts, miRNAs regulate …
in a sequence-dependent manner. For protein-coding transcripts, miRNAs regulate …
Reduced polyphenol oxidase gene expression and enzymatic browning in potato (Solanum tuberosum L.) with artificial microRNAs
M Chi, B Bhagwat, WD Lane, G Tang, Y Su, R Sun… - BMC Plant …, 2014 - Springer
Background Polyphenol oxidase (PPO), often encoded by a multi-gene family, causes
oxidative browning, a significant problem in many food products. Low-browning potatoes …
oxidative browning, a significant problem in many food products. Low-browning potatoes …
Membrane destruction-mediated antibacterial activity of tungsten disulfide (WS 2)
The antibacterial activities of tungsten disulfide (WS2) nanosheets against two
representative bacterial strains: Gram-negative Escherichia coli (E. coli) and Gram-positive …
representative bacterial strains: Gram-negative Escherichia coli (E. coli) and Gram-positive …