[Retracted] Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential

J Sharifi-Rad, C Quispe, CMS Castillo… - Oxidative medicine …, 2022 - Wiley Online Library
Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary
metabolite in many plant taxa. EA content is considerable in pomegranate (Punica granatum …

A pharmacological update of ellagic acid

JL Ríos, RM Giner, M Marín, MC Recio - Planta medica, 2018 - thieme-connect.com
Ellagic acid is a common metabolite present in many medicinal plants and vegetables. It is
present either in free form or as part of more complex molecules (ellagitannins), which can …

Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection

WR García-Niño, C Zazueta - Pharmacological Research, 2015 - Elsevier
Traditional drugs or therapies rarely have effects on regression of chronic liver diseases,
which result in many cases from sustained oxidative stress. In recent years, ellagic acid (EA) …

Ellagic acid, an NF-κB inhibitor, ameliorates renal function in experimental diabetic nephropathy

A Ahad, AA Ganai, M Mujeeb, WA Siddiqui - Chemico-Biological …, 2014 - Elsevier
Diabetic nephropathy (DN) is a serious complication confronted by diabetic patients.
Available data indicate that the development of DN is linked to inflammation. In this context …

Ellagic acid in suppressing in vivo and in vitro oxidative stresses

A Zeb - Molecular and Cellular Biochemistry, 2018 - Springer
Oxidative stress is a biological condition produced by a variety of factors, causing several
chronic diseases. Oxidative stress was, therefore, treated with natural antioxidants, such as …

Unlocking the Therapeutic Potential of Ellagic Acid for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis

T Senavirathna, A Shafaei, R Lareu, L Balmer - Antioxidants, 2024 - mdpi.com
Obesity is in epidemic proportions in many parts of the world, contributing to increasing rates
of non-alcoholic fatty liver disease (NAFLD). NAFLD represents a range of conditions from …

Ellagic acid ameliorates hexavalent chromium-induced renal toxicity by attenuating oxidative stress, suppressing TNF-α and protecting mitochondria

MY Cuevas-Magaña, CC Vega-García… - Toxicology and applied …, 2022 - Elsevier
Nephrotoxicity is an important adverse effect of oxidative stress induced by hexavalent
chromium [Cr (VI)]. The effect of ellagic acid, a dietary polyphenolic compound with potent …

Protective role of zinc in nickel induced hepatotoxicity in rats

P Sidhu, ML Garg, DK Dhawan - Chemico-Biological Interactions, 2004 - Elsevier
This study was planned to determine the protective role of zinc, if any, in attenuating the
toxicity induced by nickel sulfate in rat liver. Female Sprague Dawley (SD) rats received …

Effect of ellagic acid on cyclosporine A‐induced oxidative damage in the liver of rats

L Pari, R Sivasankari - Fundamental & clinical pharmacology, 2008 - Wiley Online Library
Cyclosporine A (CsA) is an immunosuppressor, which is most frequently used in the
transplant surgery and in the treatment of autoimmune diseases. It has been shown that CsA …

Nigella sativa (black cumin) ameliorates potassium bromate-induced early events of carcinogenesis: diminution of oxidative stress

N Khan, S Sharma, S Sultana - Human & experimental …, 2003 - journals.sagepub.com
Potassium bromate (KBrO3) is a potent nephrotoxic agent. In this paper, we report the
chemopreventive effect ofNigella sativa (black cumin) on KBrO3-mediated renal oxidative …