[HTML][HTML] The interaction between ferroptosis and lipid metabolism in cancer
D Li, Y Li - Signal transduction and targeted therapy, 2020 - nature.com
Ferroptosis is a new form of programmed cell death characterized by the accumulation of
iron-dependent lethal lipid peroxides. Recent discoveries have focused on alterations that …
iron-dependent lethal lipid peroxides. Recent discoveries have focused on alterations that …
Anti-inflammatory and M2 macrophage polarization-promoting effect of mesenchymal stem cell-derived exosomes
M Arabpour, A Saghazadeh, N Rezaei - International …, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells beneficial in regenerative medicine
and tissue repair. The therapeutic potential of MSCs for inflammatory diseases and …
and tissue repair. The therapeutic potential of MSCs for inflammatory diseases and …
[HTML][HTML] Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease
Mononuclear phagocytes (MNPs) encompass dendritic cells, monocytes, and macrophages
(MoMac), which exhibit antimicrobial, homeostatic, and immunoregulatory functions. We …
(MoMac), which exhibit antimicrobial, homeostatic, and immunoregulatory functions. We …
Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2
Background Macrophages are innate immune cells with diverse functional and molecular
phenotypes. This diversity is largely unexplored at the level of single-cell proteomes …
phenotypes. This diversity is largely unexplored at the level of single-cell proteomes …
COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
To investigate the immune response and mechanisms associated with severe coronavirus
disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal …
disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal …
Exosome-mediated genetic reprogramming of tumor-associated macrophages by exoASO-STAT6 leads to potent monotherapy antitumor activity
S Kamerkar, C Leng, O Burenkova, SC Jang… - Science …, 2022 - science.org
Effectiveness of checkpoint immunotherapy in cancer can be undermined by
immunosuppressive tumor-associated macrophages (TAMs) with an M2 phenotype …
immunosuppressive tumor-associated macrophages (TAMs) with an M2 phenotype …
Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics
Major aims of single-cell proteomics include increasing the consistency, sensitivity and
depth of protein quantification, especially for proteins and modifications of biological interest …
depth of protein quantification, especially for proteins and modifications of biological interest …
Cigarette smoke exposure and alveolar macrophages: mechanisms for lung disease
Cigarette smoking is the leading cause of preventable death worldwide. It causes chronic
lung disease and predisposes individuals to acute lung injury and pulmonary infection …
lung disease and predisposes individuals to acute lung injury and pulmonary infection …
Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
Y Lin, J Xu, H Lan - Journal of hematology & oncology, 2019 - Springer
Tumor metastasis is a major contributor to the death of cancer patients. It is driven not only
by the intrinsic alterations in tumor cells, but also by the implicated cross-talk between …
by the intrinsic alterations in tumor cells, but also by the implicated cross-talk between …
The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1
H Li, Y **ao, Q Li, J Yao, X Yuan, Y Zhang, X Yin… - Cancer cell, 2022 - cell.com
Reinvigoration of antitumor immunity remains an unmet challenge. Our retrospective
analyses revealed that cancer patients who took antihistamines during immunotherapy …
analyses revealed that cancer patients who took antihistamines during immunotherapy …